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CNS 1102

Known as: CNS-1102 
 
National Institutes of Health

Papers overview

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2010
2010
Background and Purpose— Although caffeinol (a combination of a low dose of caffeine and ethanol) was shown to robustly reduce… Expand
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Highly Cited
2006
Highly Cited
2006
Exposure to non-nutritional food additives during the critical development window has been implicated in the induction and… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND PURPOSE Aptiganel (CNS 1102) is a selective, noncompetitive antagonist that acts on the ion channel associated… Expand
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Highly Cited
1996
Highly Cited
1996
We tested the hypothesis that increasing durations of focal ischemia that have been shown to result in enlargement of cortical… Expand
1995
1995
The high affinity noncompetitive N-methyl-D-aspartate receptor antagonist CNS 1102 (aptiganel hydrochloride, Cambridge… Expand
1995
1995
The excitatory amino acid antagonists are being developed as neuroprotective drugs aimed at limiting ischemic neuronal damage… Expand
1994
1994
The cerebroprotective effects of noncompetitive N-methyl- D -aspartate (NMDA) antagonists are well documented in animal focal… Expand
Highly Cited
1994
Highly Cited
1994
This study explored the correlation between duration of focal ischemia and infarct volume in spontaneously hypertensive rats as a… Expand
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Highly Cited
1994
Highly Cited
1994
To identify the temperature dependent change of the apparent diffusion coefficient (ADC) of water in brain tissue, the ADC values… Expand
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Highly Cited
1993
Highly Cited
1993
Background and Purpose Diffusion magnetic resonance imaging (MRI) can quantitatively detect focal ischemic injury within minutes… Expand
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