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  • Jonathan Emberson, Kennedy R. Lees, +27 authors Werner Hacke
  • Medicine
  • The Lancet
  • 2014 (First Publication: 28 November 2014)
  • Summary Background Alteplase is effective for treatment of acute ischaemic stroke but debate continues about its use after longer times since stroke onset, in older patients, and among patients whoExpand
    BACKGROUND Early administration of intravenous recombinant tissue plasminogen activator (rt-PA) after ischaemic stroke improves outcome. Previous analysis of combined data from individual patientsExpand
  • H. Markus, D. Droste, +4 authors E. Ringelstein
  • Medicine
  • Circulation
  • 2005 (First Publication: 3 May 2005)
  • Background—Evidence for efficacy of dual antiplatelet therapy in stroke is limited. Symptomatic carotid stenosis patients are at high risk of early recurrent stroke. In this group, asymptomaticExpand
  • N. Wahlgren, N. Ahmed, +16 authors G. Vanhooren
  • Medicine
  • Stroke
  • 2008 (First Publication: 1 December 2008)
  • Background and Purpose— The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that theExpand