apoptolidin

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2015
01219972015

Papers overview

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2009
2009
We report the application of peptide-based catalysts to the site-selective modification of apoptolidin A (1), an agent that… (More)
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2009
2009
A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A has been completed. The key… (More)
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2007
2007
The isolation, characterization, and preliminary biological activity of apoptolidin D, a new apoptolidin that exhibits anti… (More)
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2006
2006
[structure: see text] Apoptolidin (1) exhibits potent and highly selective apoptosis inducing activity against sensitive cancer… (More)
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2003
2003
Oxidative cleavage of the C-20/C-21 bond in apoptolidin (1) provides two fragments of similar complexity, facilitating a divide… (More)
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2003
2003
A general strategy for the total synthesis of the antitumor agent apoptolidin (1) is proposed, and the chemical synthesis of the… (More)
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2002
2002
[formula: see text] Isoapoptolidin was isolated from crude fermentation extracts of the apoptolidin-producing microorganism… (More)
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2002
2002
[formula: see text] Apoptolidin (1) is a novel oncolytic lead that induces apoptosis in transformed cell lines with exceptional… (More)
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2001
2001
BACKGROUND Apoptolidin is a macrolide originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K… (More)
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1997
1997
Nocardiopsis sp. was found to produce a new active compound designated apoptolidin (Fig. 1). In this report, we describe the… (More)
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