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apoptolidin
Â
National Institutes of Health
Topic mentions per year
Topic mentions per year
1997-2015
0
1
2
1997
2015
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Macrolides
Related mentions per year
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1958-2018
1960
1980
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2020
apoptolidin
Macrolides
Papers overview
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2009
2009
An approach to the site-selective diversification of apoptolidin A with peptide-based catalysts.
Chad A Lewis
,
Kate E. Longcore
,
Scott J Miller
,
Paul A Wender
Journal of natural products
2009
We report the application of peptide-based catalysts to the site-selective modification of apoptolidin A (1), an agent that…Â
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2009
2009
Total synthesis of apoptolidin A.
Michael T Crimmins
,
Hamish S Christie
,
Alan E Long
,
Kleem Chaudhary
Organic letters
2009
A highly convergent, enantioselective total synthesis of the potent antitumor agent apoptolidin A has been completed. The key…Â
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2007
2007
Isolation, structure determination, and anti-cancer activity of apoptolidin D.
Paul A Wender
,
Kate E. Longcore
Organic letters
2007
The isolation, characterization, and preliminary biological activity of apoptolidin D, a new apoptolidin that exhibits anti…Â
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2006
2006
Correlation of F0F1-ATPase inhibition and antiproliferative activity of apoptolidin analogues.
Paul A Wender
,
Orion D Jankowski
,
Kate E. Longcore
,
Elie A Tabet
,
Haruo Seto
,
Taijiro Tomikawa
Organic letters
2006
[structure: see text] Apoptolidin (1) exhibits potent and highly selective apoptosis inducing activity against sensitive cancer…Â
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2003
2003
Facile synthetic access to and biological evaluation of the macrocyclic core of apoptolidin.
Paul A Wender
,
Orion D Jankowski
,
Elie A Tabet
,
Haruo Seto
Organic letters
2003
Oxidative cleavage of the C-20/C-21 bond in apoptolidin (1) provides two fragments of similar complexity, facilitating a divide…Â
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2003
2003
Total synthesis of apoptolidin: construction of enantiomerically pure fragments.
Kyriacos C. Nicolaou
,
Konstantina C. Fylaktakidou
,
+7 authors
Kazuyuki Sugita
Journal of the American Chemical Society
2003
A general strategy for the total synthesis of the antitumor agent apoptolidin (1) is proposed, and the chemical synthesis of the…Â
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2002
2002
Toward a stable apoptolidin derivative: identification of isoapoptolidin and selective deglycosylation of apoptolidin.
James D Pennington
,
Howard J. Williams
,
Arthur R. Salomon
,
Gary A. Sulikowski
Organic letters
2002
[formula: see text] Isoapoptolidin was isolated from crude fermentation extracts of the apoptolidin-producing microorganism…Â
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2002
2002
Isoapoptolidin: structure and activity of the ring-expanded isomer of apoptolidin.
Paul A Wender
,
Aaron V Gulledge
,
Orion D Jankowski
,
Haruo Seto
Organic letters
2002
[formula: see text] Apoptolidin (1) is a novel oncolytic lead that induces apoptosis in transformed cell lines with exceptional…Â
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2001
2001
Apoptolidin, a selective cytotoxic agent, is an inhibitor of F0F1-ATPase.
Arthur R. Salomon
,
David Voehringer
,
Leonore Herzenberg
,
Charu Khosla
Chemistry & biology
2001
BACKGROUND Apoptolidin is a macrolide originally identified on the basis of its ability to selectively kill E1A and E1A/E1B19K…Â
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1997
1997
Apoptolidin, a new apoptosis inducer in transformed cells from Nocardiopsis sp.
J. W. Kim
,
H. Adachi
,
Kazuo Shin-Ya
,
Yoichi Hayakawa
,
H Seto
The Journal of antibiotics
1997
Nocardiopsis sp. was found to produce a new active compound designated apoptolidin (Fig. 1). In this report, we describe the…Â
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