apixaban

Known as: 1H-Pyrazolo(3,4-c)pyridine-3-carboxamide, 4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxo-1-piperidinyl)phenyl)-, apixabanum, apixabán 
An orally active inhibitor of coagulation factor Xa with anticoagulant activity. Apixaban directly inhibits factor Xa, thereby interfering with the… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND Apixaban, an oral factor Xa inhibitor administered in fixed doses, may simplify the treatment of venous… (More)
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Highly Cited
2013
Highly Cited
2013
BACKGROUND Apixaban, an oral factor Xa inhibitor that can be administered in a simple, fixed-dose regimen, may be an option for… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Vitamin K antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Apixaban, an oral, direct factor Xa inhibitor, may reduce the risk of recurrent ischemic events when added to… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Vitamin K antagonists have been shown to prevent stroke in patients with atrial fibrillation. However, many patients… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND The efficacy and safety of prolonging prophylaxis for venous thromboembolism in medically ill patients beyond hospital… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND There are various regimens for thromboprophylaxis after hip replacement. Low-molecular-weight heparins such as… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Low-molecular-weight heparins such as enoxaparin are preferred for prevention of venous thromboembolism after major… (More)
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Highly Cited
2009
Highly Cited
2009
The metabolism and disposition of [(14)C]apixaban, an orally bioavailable, highly selective, and direct acting/reversible factor… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND The optimal strategy for thromboprophylaxis after major joint replacement has not been established. Low-molecular… (More)
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