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Factor Xa inhibitors

Known as: Inhibitors, Factor Xa 
Endogenous factors and drugs that inhibit or block the activity of FACTOR XA.
National Institutes of Health

Papers overview

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Highly Cited
2019
Highly Cited
2019
Background Andexanet alfa is a modified recombinant inactive form of human factor Xa developed for reversal of factor Xa… Expand
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Highly Cited
2017
2017
2017
BackgroundThere is considerable debate regarding the ideal agent for venous thromboembolism (VTE) prophylaxis after TKA. Numerous… Expand
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Highly Cited
2016
Highly Cited
2016
BACKGROUND Andexanet alfa (andexanet) is a recombinant modified human factor Xa decoy protein that has been shown to reverse the… Expand
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Review
2016
Review
2016
ABSTRACT Andexanet alfa is a specific reversal agent for Factor Xa inhibitors. The molecule is a recombinant protein analog of… Expand
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Review
2012
Review
2012
Vitamin K antagonists, such as warfarin, have been the mainstay of oral anticoagulation for many decades. Although effective… Expand
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Highly Cited
2009
Highly Cited
2009
Summary.  Background: Apixaban is an oral, direct factor Xa (FXa) inhibitor in late‐stage clinical development. This study… Expand
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Review
2002
Review
2002
Despite currently available antithrombotic therapies, venous thromboembolism (VTE) remains a major cause of morbidity and… Expand
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Highly Cited
2002
Highly Cited
2002
DPC423 [1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2′-(methylsulfonyl)[1,1′-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5… Expand
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Highly Cited
1991
Highly Cited
1991
An in vivo thromboplastin (TP)-induced venous stasis thrombosis model in rabbits was used to compare the efficacy of standard… Expand
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