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Antithrombin III

Known as: Antithrombin III [Chemical/Ingredient], Heparin Co-Factor I, SERPINC1 
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (27)

ATrynAtenativKyberninPB 145
Antithrombin Ag:ACnc:Pt:PPP:Qn:IAAntithrombin III MeasurementAntithrombin III, HumanBlood coagulation

Broader (2)

AntithrombinsFactor Xa inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy
Background Current hemophilia treatment involves frequent intravenous infusions of clotting factors, which is associated with… 
Highly Cited
2010
Highly Cited
2010
EFNS guideline on the treatment of cerebral venous and sinus thrombosis in adult patients
Background:  Cerebral venous and sinus thrombosis (CVST) is a rather rare disease which accounts for <1% of all strokes… 
Highly Cited
2001
Highly Cited
2001
Presumed pre‐ or perinatal arterial ischemic stroke: Risk factors and outcomes
A subgroup of children with arterial ischemic stroke in the pre‐ or perinatal period present with delayed diagnosis. We… 
Highly Cited
2001
Highly Cited
2001
Thrombogenesis in sickle cell disease.
Thirty-three subjects with sickle cell disease (SCD), 11 during episodes of pain and 22 during periods without pain, were… 
Highly Cited
1999
Highly Cited
1999
Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors…
The reported incidence of thromboembolism in children with acute lymphoblastic leukemia (ALL) treated with L-asparaginase… 
Highly Cited
1999
Highly Cited
1999
The incidence of venous thromboembolism in asymptomatic carriers of a deficiency of antithrombin, protein C, or protein S: a prospective cohort study.
Deficiencies of antithrombin, protein C, and protein S are associated with an increased risk of venous thromboembolism. The… 
Highly Cited
1997
Highly Cited
1997
Hypercoagulability in patients with primary biliary cirrhosis and primary sclerosing cholangitis evaluated by thrombelastography.
Highly Cited
1994
Highly Cited
1994
The intact and cleaved human antithrombin III complex as a model for serpin–proteinase interactions
Antithrombin is a member of the serine proteinase inhibitor (serpin) family which contain a flexible reactive site loop that… 
Highly Cited
1982
Highly Cited
1982
Further characterization of the antithrombin-binding sequence in heparin.
Highly Cited
1974
Highly Cited
1974
Abnormal Antithrombin III (Antithrombin III ‘Budapest’) as a Cause of a Familial Thrombophilia
Summary A family with a high incidence of spontaneous thromboembolism has been investigated and those members affected were found… 
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