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Antithrombin III

Known as: Antithrombin III [Chemical/Ingredient], Heparin Co-Factor I, SERPINC1 
Antithrombin-III (464 aa, ~53 kDa) is encoded by the human SERPINC1 gene. This protein is involved in the negative regulation of serine proteinase… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (27)

ATrynAtenativKyberninPB 145
Antithrombin Ag:ACnc:Pt:PPP:Qn:IAAntithrombin III MeasurementAntithrombin III, HumanBlood coagulation

Broader (2)

AntithrombinsFactor Xa inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2000
Highly Cited
2000
Prothrombotic risk factors in children with spontaneous venous thrombosis and their asymptomatic parents: a family study.
Highly Cited
2000
Highly Cited
2000
Role of Arginine 129 in Heparin Binding and Activation of Antithrombin*
The contribution of Arg129 of the serpin, antithrombin, to the mechanism of allosteric activation of the protein by heparin was… 
Review
1999
Review
1999
Activated Protein C Resistance and Thrombosis: Molecular Mechanisms of Hypercoagulable State Due to FVR506Q Mutation
Inherited resistance to activated protein C (APC) is the most common genetic risk factor of venous thrombosis. It is caused by a… 
Highly Cited
1993
Highly Cited
1993
Immunologic evidence for insertion of the reactive-bond loop of antithrombin into the A beta-sheet of the inhibitor during trapping of target proteinases.
Identical or highly similar antigenic determinants, not present in the intact inhibitor, were induced in antithrombin on cleavage… 
Highly Cited
1982
Highly Cited
1982
A new familial variant of antithrombin III: ‘Antithrombin III Paris’
Summary. A 59‐year‐old woman presented a recurrent history of thromboembolism. A qualitative defect of antithrombin III (AT III… 
Highly Cited
1980
Highly Cited
1980
Heterogeneity of the "Classical" Antithrombin III Deficiency
Summary We investigated two thrombophilia families with the "classical" type of antithrombin III deficiency, i.e., with a low… 
Highly Cited
1978
Highly Cited
1978
Familial thrombosis: inherited deficiency of antithrombin III.
Several members of a family living on the west coast of Scotland and on one of the islands off the coast had serious thrombotic… 
Highly Cited
1976
Highly Cited
1976
Characterization of human, bovine, and horse antithrombin III.
A comparison of the physical-chemical properties of human, bovine, and horse antithrombin III has been made. These three plasma… 
Highly Cited
1975
Highly Cited
1975
Action of heparin on thrombin-antithrombin reaction.
Highly Cited
1974
Highly Cited
1974
Abnormal Antithrombin III (Antithrombin III ‘Budapest’) as a Cause of a Familial Thrombophilia
Summary A family with a high incidence of spontaneous thromboembolism has been investigated and those members affected were found… 
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