Semantic Scholar uses AI to extract papers important to this topic.
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures have been investigated in the… Expand A large number of structurally diverse natural compounds containing azole nucleus constitute an important class of biologically… Expand This Perspective summarises the chemistry of the pyrazole ring, and reviews the metal coordination modes adopted by 1H-pyrazoles… Expand Canonical transient receptor potential (TRPC) channels control influxes of Ca2+ and other cations that induce diverse cellular… Expand A series of substituted chalcones and their corresponding pyrazoles were synthesized and evaluated for in vitro cytotoxic… Expand This paper details the copper-catalyzed N-arylation of pi-excessive nitrogen heterocycles. The coupling of either aryl iodides or… Expand A convenient one-pot procedure for the preparation of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds generated in situ… Expand We have found that certain tetrasubstituted pyrazoles are high-affinity ligands for the estrogen receptor (ER) (Fink et al. Chem… Expand The antimycotic clotrimazole, a potent inhibitor of the intermediate-conductance calcium-activated K(+) channel, IKCa1, is in… Expand