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amino acid homeostasis
Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell. [PMID:19955263]
National Institutes of Health
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Highly Cited
2018
Highly Cited
2018
Amino Acid Transport Across the Mammalian Intestine.
S. Bröer
,
Stephen J. Fairweather
Comprehensive Physiology
2018
Corpus ID: 56485230
The small intestine mediates the absorption of amino acids after ingestion of protein and sustains the supply of amino acids to…
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Highly Cited
2017
Highly Cited
2017
mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient
Gregory A. Wyant
,
Monther Abu-Remaileh
,
+5 authors
D. Sabatini
Cell
2017
Corpus ID: 206566515
Highly Cited
2015
Highly Cited
2015
GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2
Jiangbin Ye
,
Wilhelm Palm
,
+5 authors
C. Thompson
Genes & Development
2015
Corpus ID: 20129199
In this study, Ye et al. show that activation of GCN2, an amino acid-sensing kinase, during amino acid deprivation leads to ATF4…
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Highly Cited
2012
Highly Cited
2012
LAAT-1 Is the Lysosomal Lysine/Arginine Transporter That Maintains Amino Acid Homeostasis
B. Liu
,
Hongwei Du
,
R. Rutkowski
,
A. Gartner
,
Xiaochen Wang
Science
2012
Corpus ID: 13932774
Lysosomal Amino Acid Transporter Cystinosis is characterized by intralysosomal accumulation of free cystine, which results in age…
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Highly Cited
2012
Highly Cited
2012
Siliques Are Red1 from Arabidopsis Acts as a Bidirectional Amino Acid Transporter That Is Crucial for the Amino Acid Homeostasis of Siliques1[W][OA]
Friederike Ladwig
,
M. Stahl
,
+5 authors
Wolfgang Koch
Plant Physiology
2012
Corpus ID: 22114007
Many membrane proteins are involved in the transport of nutrients in plants. While the import of amino acids into plant cells is…
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Highly Cited
2012
Highly Cited
2012
T‐type amino acid transporter TAT1 (Slc16a10) is essential for extracellular aromatic amino acid homeostasis control
Luca Mariotta
,
T. Ramadan
,
+7 authors
F. Verrey
Journal of Physiology
2012
Corpus ID: 24181982
• The amino acid (AA) transporter TAT1 (Slc16A10) mediates facilitated diffusion of aromatic AAs (AAAs) across membranes…
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Highly Cited
2011
Highly Cited
2011
Perturbation of Arabidopsis Amino Acid Metabolism Causes Incompatibility with the Adapted Biotrophic Pathogen Hyaloperonospora arabidopsidis[C][W][OA]
Johannes Stuttmann
,
Hans-Michael Hubberten
,
+6 authors
J. Parker
The Plant Cell
2011
Corpus ID: 6812135
This work identified two different Arabidopsis mutants that have reduced susceptibility to an infectious biotrophic pathogen due…
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Review
2008
Review
2008
Aberrant insulin receptor signaling and amino acid homeostasis as a major cause of oxidative stress in aging.
W. Dröge
,
R. Kinscherf
Antioxidants and Redox Signaling
2008
Corpus ID: 40580271
The mechanisms leading to the increase in free radical-derived oxidative stress in "normal aging" remains obscure. Here we…
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Highly Cited
2006
Highly Cited
2006
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body.
Karine Lindmo
,
A. Simonsen
,
A. Brech
,
K. Finley
,
T. Rusten
,
H. Stenmark
Experimental Cell Research
2006
Corpus ID: 31902905
Review
1997
Review
1997
Molecular characteristics of mammalian and insect amino acid transporters: implications for amino acid homeostasis.
M. Castagna
,
C. Shayakul
,
D. Trotti
,
V. Sacchi
,
W. R. Harvey
,
M. Hediger
Journal of Experimental Biology
1997
Corpus ID: 6423261
In mammalian cells, the uptake of amino acids is mediated by specialized, energy-dependent and passive transporters with…
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