amatuximab

Known as: Anti-Mesothelin Monoclonal Antibody MORAb-009, Immunoglobulin G1, Anti-(mesothelin) (Human-Mouse Monoclonal MORAb-009 Heavy Chain), Disulfide with Human-Mouse Monoclonal MORAb-009 Kappa-Chain, Dimer 
A chimeric IgG1 monoclonal antibody against human mesothelin with potential anti-tumor activity. Amatuximab specifically targets mesothelin, a cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2017
01220102017

Papers overview

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2018
2018
The tumor-shed antigen CA125 has recently been found to bind certain monoclonal antibodies (mAbs) and suppress immune-effector… (More)
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Review
2017
Review
2017
Mesothelin (MSLN) is considered a promising target for cancer therapy. Originally extracted in 1992 after the immunization of… (More)
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Review
2017
Review
2017
Malignant pleural mesothelioma(MPM)is a highly aggressive tumor with a poor prognosis and an increasing incidence worldwide. The… (More)
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2016
2016
To characterize amatuximab pharmacokinetics (PK) and the relationship of amatuximab exposure with response in patients with… (More)
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Review
2016
Review
2016
Mesothelin is a tumor antigen that is highly expressed in many human cancers, including malignant mesothelioma and pancreatic… (More)
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2015
2015
Amatuximab is a chimeric high-affinity monoclonal IgG1/k antibody targeting mesothelin that is being developed for treatment of… (More)
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2015
2015
OBJECTIVES To investigate the effect of the injection dose of MORAb-009 (amatuximab, an anti-mesothelin monoclonal antibody), the… (More)
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2014
2014
Amatuximab is a chimeric monoclonal antibody that targets mesothelin, which is expressed in virtually all mesotheliomas and… (More)
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2014
Review
2014
PURPOSE Amatuximab is a chimeric monoclonal antibody to mesothelin, a cell surface glycoprotein highly expressed in malignant… (More)
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2013
Review
2013
Mesothelin, a glycosylphosphatidylinositol (GPI) anchored cell surface protein, is a potential target for antibody-based cancer… (More)
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