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amatuximab

Known as: Anti-Mesothelin Monoclonal Antibody MORAb-009, Immunoglobulin G1, Anti-(mesothelin) (Human-Mouse Monoclonal MORAb-009 Heavy Chain), Disulfide with Human-Mouse Monoclonal MORAb-009 Kappa-Chain, Dimer 
A chimeric IgG1 monoclonal antibody against human mesothelin with potential anti-tumor activity. Amatuximab specifically targets mesothelin, a cell… Expand
National Institutes of Health

Papers overview

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2017
2017
Human malignant mesothelioma is a chemoresistant tumour that develops from mesothelial cells, commonly associated with asbestos… Expand
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Review
2016
Review
2016
Mesothelin is a tumor antigen that is highly expressed in many human cancers, including malignant mesothelioma and pancreatic… Expand
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2016
2016
Abstract: Background Monoclonal antibodies have become attractive clinical anti-cancer drugs in the last 3 decades due to their… Expand
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2016
2016
AbstractPurpose To characterize amatuximab pharmacokinetics (PK) and the relationship of amatuximab exposure with response in… Expand
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2015
2015
Amatuximab is a chimeric high-affinity monoclonal IgG1/k antibody targeting mesothelin that is being developed for treatment of… Expand
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2014
2014
SummaryAmatuximab is a chimeric monoclonal antibody that targets mesothelin, which is expressed in virtually all mesotheliomas… Expand
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Review
2014
Review
2014
PURPOSE Amatuximab is a chimeric monoclonal antibody to mesothelin, a cell surface glycoprotein highly expressed in malignant… Expand
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2012
2012
7030 Background: Amatuximab (MORAb-009) is a chimeric monoclonal antibody to mesothelin, a cell surface glycoprotein highly… Expand
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2011
2011
INTRODUCTION Radiolabeling of a monoclonal antibody (mAb) with a metallic radionuclide requires the conjugation of a bifunctional… Expand
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1982
1982
This study demonstrates that an uncharacterized soluble factor produced in concanavalin A-induced rat spleen cell suspensions has… Expand
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