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alpidem

 
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
The flow of information between chemical and biological research can present a bottleneck in pharmaceutical research. Tools that… Expand
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Highly Cited
2012
Highly Cited
2012
A variety of functionalized imidazo[1,2-a]pyridines have been synthesized through a one-pot, room temperature, and reagent-free… Expand
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Highly Cited
2010
Highly Cited
2010
Imidazopyridine is an important pharmacophore widely found in many biologically active compounds.[i] Particularly, imidazo[1,2-a… Expand
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Highly Cited
2007
Highly Cited
2007
Abstract The novel use of zinc chloride to catalyze the one-pot, three component synthesis of imidazo[1,2- a ]pyridines from a… Expand
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Highly Cited
2001
Highly Cited
2001
Whereas alpidem is hepatotoxic, zolpidem is not. Despite closely related chemical structures, alpidem, but not zolpidem, is a… Expand
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Highly Cited
1996
Highly Cited
1996
Alpidem (1), the anxiolytic imidazopyridine, has nanomolar binding affinity for both the central benzodiazepine receptor (CBR… Expand
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Highly Cited
1993
Highly Cited
1993
Pharmacological characterization of [3H]benzodiazepine binding to membrane preparations of adult rat hippocampus and neonatal rat… Expand
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Highly Cited
1993
Highly Cited
1993
A rapid twin-column gas chromatographic (GC) method for simultaneous screening and determination of commonly prescribed… Expand
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Highly Cited
1993
Highly Cited
1993
When given the opportunity to choose between a novel and a familiar compartment (free-exploratory paradigm), BALB/c mice… Expand
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Highly Cited
1991
Highly Cited
1991
gamma-Aminobutyric acid (GABA)-activated Cl- currents in neonatal rat cortical neurons and in cultured cells engineered for the… Expand
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