alpha 1-proteinase inhibitor, human

Known as: Alpha-1 Proteinase Inhibitor, Human, .alpha.1-proteinase Inhibitor Human, alpha1-proteinase inhibitor human 
Human serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and anti-inflammatory activity. Upon… (More)
National Institutes of Health

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Review
2008
Review
2008
Alpha-1-antitrypsin deficiency (AATD) is a genetic disorder that manifests as pulmonary emphysema, liver cirrhosis and, rarely… (More)
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Highly Cited
2007
Highly Cited
2007
UNLABELLED The differentiation capacity of human embryonic stem cells (hESCs) holds great promise for therapeutic applications… (More)
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Highly Cited
2006
Highly Cited
2006
alpha-1 Antitrypsin (A1AT) is an abundant circulating serpin with a postulated function in the lung of potently inhibiting… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVE The purpose of this study was to investigate the inflammatory state in obese women displaying the "metabolically… (More)
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Highly Cited
1997
Highly Cited
1997
The Rho GDP dissociation inhibitor (GDI) forms a complex with the GDP-bound form of the Rho family small G proteins and inhibits… (More)
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Highly Cited
1992
Highly Cited
1992
Most northern Europeans have only the normal M form of the plasma protease inhibitor alpha 1-antitrypsin, but some 4% are… (More)
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Review
1988
Review
1988
Alpha-1-antitrypsin (A1AT) deficiency is an autosomal hereditary disorder associated with a major reduction in serum A1AT levels… (More)
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Highly Cited
1987
Highly Cited
1987
In patients with alpha 1-antitrypsin deficiency, the development of emphysema is believed to be caused by the unchecked action of… (More)
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Highly Cited
1986
Highly Cited
1986
Triggered human neutrophils were able to maintain released elastase in an active form in the presence of purified alpha-1… (More)
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1982
1982
When alpha-1-PI is oxidized, it loses its ability to inhibit porcine elastase, although it retains its TIC. Therefore the ratio… (More)
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