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alpha 1-proteinase inhibitor, human

Known as: Alpha-1 Proteinase Inhibitor, Human, .alpha.1-proteinase Inhibitor Human, alpha1-proteinase inhibitor human 
Human serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and anti-inflammatory activity. Upon… 
National Institutes of Health

Related topics

Related topics

11 relations
Alpha-1-antitrypsin measurementDrug AllergyNCIt Antineoplastic Agent TerminologySERPINA1 gene

Narrower (2)

GlassiaProlastin

Broader (1)

alpha 1-Antitrypsin

Papers overview

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Highly Cited
2004
Highly Cited
2004
Regulation of Antiprotease and Antimicrobial Protein Secretion by Airway Submucosal Gland Serous Cells*
Airway submucosal gland serous cells express the cystic fibrosis transmembrane conductance regulator (CFTR) and secrete… 
Highly Cited
1998
Highly Cited
1998
Potato Carboxypeptidase Inhibitor, a T-knot Protein, Is an Epidermal Growth Factor Antagonist That Inhibits Tumor Cell Growth*
Epidermal growth factor (EGF) and its receptor (EGFR) are involved in many aspects of the development of carcinomas, including… 
Highly Cited
1996
Highly Cited
1996
Degradation of host protease inhibitors and activation of plasminogen by proteolytic enzymes from Porphyromonas gingivalis and Treponema denticola.
Bacterial proteases may participate in the pathogenesis of periodontal diseases through their action on host proteins. In the… 
Highly Cited
1995
Highly Cited
1995
Human neutrophils store type II 14-kDa phospholipase A2 in granules and secrete active enzyme in response to soluble stimuli.
Although "secretory" type II 14-kDa phospholipase A2 (sPLA2) activity has been described in neutrophils, direct evidence of… 
Highly Cited
1994
Highly Cited
1994
Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis.
We have reported that three different Fn fragments (Fn-f) added to bovine articular cartilage cultured in serum-free DMEM cause… 
Highly Cited
1990
Highly Cited
1990
Recombinant chymotrypsin inhibitor 2: expression, kinetic analysis of inhibition with alpha-chymotrypsin and wild-type and mutant subtilisin BPN', and protein engineering to investigate inhibitory…
The serine protease inhibitor chymotrypsin inhibitor 2 (CI2 or BSPI2) has been expressed in Escherichia coli with the pINIIIompA3… 
Highly Cited
1986
Highly Cited
1986
A new member of the plasma protease inhibitor gene family.
A 2.1-kb cDNA clone representing a new member of the protease inhibitor family was isolated from a human liver cDNA library. The… 
Highly Cited
1983
Highly Cited
1983
Inhibition of microbial IgA proteases by human secretory IgA and serum.
Highly Cited
1981
Highly Cited
1981
Enzymatic reduction of oxidized alpha-1-proteinase inhibitor restores biological activity.
The major serum inhibitor of proteolytic activity, alpha-1-proteinase inhibitor (alpha-1-PI), (or alpha-1-antitrypsin) can be… 
Highly Cited
1979
Highly Cited
1979
Characterization of the inactive fragment resulting from limited proteolysis of human alpha1-proteinase inhibitor by Crotalus adamanteus proteinase II.
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