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alpha 1-proteinase inhibitor, human
Known as:
Alpha-1 Proteinase Inhibitor, Human
, .alpha.1-proteinase Inhibitor Human
, alpha1-proteinase inhibitor human
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Human serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and anti-inflammatory activity. Upon…
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National Institutes of Health
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Related topics
Related topics
11 relations
Alpha-1-antitrypsin measurement
Drug Allergy
NCIt Antineoplastic Agent Terminology
SERPINA1 gene
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Narrower (2)
Glassia
Prolastin
Broader (1)
alpha 1-Antitrypsin
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Regulation of Antiprotease and Antimicrobial Protein Secretion by Airway Submucosal Gland Serous Cells*
N. Joo
,
Dennis J Lee
,
Kimberly M Winges
,
A. Rustagi
,
J. Wine
Journal of Biological Chemistry
2004
Corpus ID: 21973822
Airway submucosal gland serous cells express the cystic fibrosis transmembrane conductance regulator (CFTR) and secrete…
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Highly Cited
1998
Highly Cited
1998
Potato Carboxypeptidase Inhibitor, a T-knot Protein, Is an Epidermal Growth Factor Antagonist That Inhibits Tumor Cell Growth*
C. Blanco-Aparicio
,
M. Molina
,
+5 authors
R. de Llorens
Journal of Biological Chemistry
1998
Corpus ID: 26716619
Epidermal growth factor (EGF) and its receptor (EGFR) are involved in many aspects of the development of carcinomas, including…
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Highly Cited
1996
Highly Cited
1996
Degradation of host protease inhibitors and activation of plasminogen by proteolytic enzymes from Porphyromonas gingivalis and Treponema denticola.
D. Grenier
Microbiology
1996
Corpus ID: 32154527
Bacterial proteases may participate in the pathogenesis of periodontal diseases through their action on host proteins. In the…
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Highly Cited
1995
Highly Cited
1995
Human neutrophils store type II 14-kDa phospholipase A2 in granules and secrete active enzyme in response to soluble stimuli.
M. D. Rosenthal
,
M. Gordon
,
E. Buescher
,
J. Slusser
,
L. Harris
,
R. Franson
Biochemical and Biophysical Research…
1995
Corpus ID: 37216205
Although "secretory" type II 14-kDa phospholipase A2 (sPLA2) activity has been described in neutrophils, direct evidence of…
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Highly Cited
1994
Highly Cited
1994
Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis.
D. Xie
,
F. Hui
,
R. Meyers
,
G. Homandberg
Archives of Biochemistry and Biophysics
1994
Corpus ID: 10562919
We have reported that three different Fn fragments (Fn-f) added to bovine articular cartilage cultured in serum-free DMEM cause…
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Highly Cited
1990
Highly Cited
1990
Recombinant chymotrypsin inhibitor 2: expression, kinetic analysis of inhibition with alpha-chymotrypsin and wild-type and mutant subtilisin BPN', and protein engineering to investigate inhibitory…
Colin Longstaff
,
Alison F. Campbell
,
A. Fersht
Biochemistry
1990
Corpus ID: 22899291
The serine protease inhibitor chymotrypsin inhibitor 2 (CI2 or BSPI2) has been expressed in Escherichia coli with the pINIIIompA3…
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Highly Cited
1986
Highly Cited
1986
A new member of the plasma protease inhibitor gene family.
H. Ragg
Nucleic Acids Research
1986
Corpus ID: 23966970
A 2.1-kb cDNA clone representing a new member of the protease inhibitor family was isolated from a human liver cDNA library. The…
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Highly Cited
1983
Highly Cited
1983
Inhibition of microbial IgA proteases by human secretory IgA and serum.
J. V. Gilbert
,
A. Plaut
,
B. Longmaid
,
M. Lamm
Molecular Immunology
1983
Corpus ID: 24235313
Highly Cited
1981
Highly Cited
1981
Enzymatic reduction of oxidized alpha-1-proteinase inhibitor restores biological activity.
W. Abrams
,
G. Weinbaum
,
L. Weissbach
,
H. Weissbach
,
N. Brot
Proceedings of the National Academy of Sciences…
1981
Corpus ID: 25044251
The major serum inhibitor of proteolytic activity, alpha-1-proteinase inhibitor (alpha-1-PI), (or alpha-1-antitrypsin) can be…
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Highly Cited
1979
Highly Cited
1979
Characterization of the inactive fragment resulting from limited proteolysis of human alpha1-proteinase inhibitor by Crotalus adamanteus proteinase II.
L. F. Kress
,
T. Kurecki
,
S. Chan
,
M. Laskowski
Journal of Biological Chemistry
1979
Corpus ID: 45225206
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