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alosetron

Known as: 2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one, alosetron [Chemical/Ingredient] 
A potent and selective 5-HT3 receptor antagonist. Alosetron blocks the actions of serotonin at 5-HT3 sites in the peripheral nervous system… 
National Institutes of Health

Related topics

Related topics

22 relations
Abdominal PainColitis, IschemicConstipationCrohn Disease

Broader (3)

CarbolinesGastrointestinal AgentsSerotonin Antagonists

Narrower (3)

GR 68755Lotronexalosetron hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
An evidence-based approach to IBS and CIC: Applying new advances to daily practice
Release Date: February 1, 2017 Expiration Date: February 1, 2018 Estimated time to complete activity: 1 hour Project ID: 5472… 
2016
2016
A Cost-Effectiveness Comparison of Alosetron, Eluxadoline, and Rifaximin in the Treatment of Irritable Bowel Syndrome with Diarrhea
1.1.    Objective: The recurrent and complex Irritable Bowel Syndrome (IBS) has major impact on healthcare cost and quality-of… 
2014
2014
A New Extractive Spectrophotometric Method for the Estimation of Alosetron.
Two simple, accurate, rapid and sensitive Methods (A and B) have been developed for the estimation of Alosetron in its… 
2014
2014
Evaluation of Alosetron Using the New FDA Composite Endpoint Demonstrates Strong Treatment Effect in Females With Severe Irritable Bowel Syndrome With Diarrhea: 1810
2014
2014
Validated Bioanalytical Method Development for the Determination of Alosetron in Human K2edta Plasma by Using LC-MS/MS
AIM: The aim of this study is to develop and validate a specific bioanalytical method by LCMS/ MS for the estimation of… 
2009
2009
Continuing Medical Education Questions: July 2009
2007
2007
Pathophysiology of Irritable bowel syndrome:The role of brain-gut axis and serotoninergic receptors
SUMMARY The last decade has been marked by substantial progress in the understanding of the pathophysiology of Irritable Bowel… 
1999
1999
CLINICAL PHARMACOLOGY OF ALOSETRON
1999
1999
THE SAFETY AND EFFICACY OF ALOSETRON, A 5-HT3 RECEPTOR ANTAGONIST, IN FEMALE IRRITABLE BOWEL SYNDROME PATIENTS
1999
1999
Treatment of female IBS patients with alosetron, a potent and selective 5HT3-receptor antagonist