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AGA technical review on irritable bowel syndrome.
TLDR
Psychosocial factors, although not part of IBS per se, have an important role in modulating the illness experience and its clinical outcome.
A System Model of Oral Glucose Absorption: Validation on Gold Standard Data
TLDR
The recent availability of Ra data is utilized, estimated with a model-independent multiple tracer technique, to formulate a system model of intestinal glucose absorption, which has important potential both in simulation contexts and in clinical studies to quantitatively characterize possible impairment of glucose absorption in particular populations such as elderly and diabetic individuals.
A randomized controlled trial of a probiotic combination VSL# 3 and placebo in irritable bowel syndrome with bloating
Abstract  Aim:  To evaluate the effects of a combination probiotic on symptoms and colonic transit in patients with irritable bowel syndrome (IBS) and significant bloating.
A placebo-controlled trial of prucalopride for severe chronic constipation.
TLDR
Over 12 weeks, prucalopride significantly improved bowel function and reduced the severity of symptoms in patients with severe chronic constipation.
A randomized controlled trial of a probiotic, VSL#3, on gut transit and symptoms in diarrhoea‐predominant irritable bowel syndrome
Aim : To investigate the effects of a probiotic formulation, VSL#3, on gastrointestinal transit and symptoms of patients with Rome II irritable bowel syndrome with predominant diarrhoea.
Fecal Lactoferrin Is a Sensitive and Specific Marker in Identifying Intestinal Inflammation
TLDR
Fecal lactoferrin is sensitive and specific for detecting inflammation in chronic IBD and may prove useful in screening for inflammation in patients presenting with abdominal pain and diarrhea.
Clinical Guideline: Management of Gastroparesis
TLDR
Current approved treatment options, including metoclopramide and gastric electrical stimulation (GES), do not adequately address clinical need and attention should be given to the development of new effective therapies for symptomatic control.
Chronic constipation.
TLDR
Constipation is more prevalent in women than in men, in nonwhites than in white persons, in children than in adults, 6 and in elderly than in younger adults.
Efficacy and safety of alosetron in women with irritable bowel syndrome: a randomised, placebo-controlled trial
TLDR
Alosetron was well tolerated and clinically effective in alleviating pain and bowel-related symptoms in this population of women with IBS.
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