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allophenylnorstatine

National Institutes of Health

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1 relation

Broader (1)

3-amino-2-hydroxy-4-phenylbutanoic acid

Papers overview

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2010
2010
Improvement of both plasmepsin inhibitory activity and antimalarial activity by 2-aminoethylamino substitution.
2004
2004
Water-soluble prodrugs of dipeptide HIV protease inhibitors based on O-->N intramolecular acyl migration: Design, synthesis and kinetic study.
2002
2002
New water-soluble prodrugs of HIV protease inhibitors based on O-->N intramolecular acyl migration.
2000
2000
Structure-activity relationship of orally potent tripeptide-based HIV protease inhibitors containing hydroxymethylcarbonyl isostere.
We designed and synthesized a new class of peptidomimetic human immunodeficiency virus protease inhibitors containing a unique… 
1998
1998
KNI‐577, a Potent Small‐Sized HIV Protease Inhibitor Based on the Dipeptide Containing the Hydroxymethylcarbonyl Isostere as an Ideal Transition‐State Mimic
The development of an effective therapeutic agent for the treatment of AIDS continues to be a challenging problem. Since the… 
Review
1996
Review
1996
Design and synthesis of substrate-based peptidomimetic human immunodeficiency virus protease inhibitors containing the hydroxymethylcarbonyl isostere.
The human immunodeficiency (HIV) codes for an aspartic protease known to be essential for retroviral maturation and replication… 
1996
1996
Solution conformations of KNI-272, a tripeptide HIV protease inhibitor designed on the basis of substrate transition state: determined by NMR spectroscopy and simulated annealing calculations.
1995
1995
In vitro anti-HIV-1 activity of HIV protease inhibitor KNI-272 in resting and activated cells: implications for its combined use with AZT or ddI.
1994
1994
Solution structure of HIV-1 protease-allophenylnorstatine derivative inhibitor complex obtained from molecular dynamics simulation.
Structures of two enzyme-inhibitor complexes of human immunodeficiency virus-1 protease with allophenylnorstatine derivatives… 
Highly Cited
1993
Highly Cited
1993
In vitro anti-human immunodeficiency virus (HIV) activities of transition state mimetic HIV protease inhibitors containing allophenylnorstatine
Transition state mimetic tripeptide human immunodeficiency virus (HIV) protease inhibitors containing allophenylnorstatine [(2S… 
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