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alicaforsen

National Institutes of Health

Papers overview

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2016
2016
Background and aims The published data about the efficacy of the intercellular adhesion molecule-1 (ICAM-1) antisense… Expand
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2013
2013
The antisense ICAM‐1 inhibitor alicaforsen has been studied in four phase 2 studies in ulcerative colitis (UC). Recruited… Expand
Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS The aim of this study was to compare the safety and efficacy of alicaforsen, a first-generation antisense… Expand
Highly Cited
2006
Highly Cited
2006
Alicaforsen is an antisense oligonucleotide inhibitor of intercellular adhesion molecule 1 protein expression with activity in… Expand
Highly Cited
2006
Highly Cited
2006
Alicaforsen is a phosphorothioate‐modified antisense oligodeoxynucleotide designed to sequence‐specifically reduce intercellular… Expand
Highly Cited
2004
Highly Cited
2004
Background : Pouchitis is the major long‐term complication of ileal pouch‐anal anastomosis for ulcerative colitis. The incidence… Expand
Highly Cited
2004
Highly Cited
2004
Objective: To evaluate the safety and efficacy of an enema formulation of alicaforsen, an antisense inhibitor of intercellular… Expand
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Highly Cited
2002
Highly Cited
2002
Background and aims: To evaluate the safety and efficacy of the intercellular adhesion molecule 1 (ICAM-1) antisense… Expand
Highly Cited
2002
Highly Cited
2002
Background and aims : To evaluate the safety, pharmacokinetics and clinical efficacy of the intercellular adhesion molecule‐1… Expand
Review
2001
Review
2001
Alicaforsen (ISIS-2302) is an RNase H-dependent antisense inhibitor of the intercellular adhesion molecule ICAM-1 under… Expand