Phosphorothioate Oligonucleotides

Known as: Oligonucleotides, Phosphorothioate, Phosphorothioate Oligonucleotide, Phosphorothioate Oligonucleotides [Chemical/Ingredient]

Modified oligonucleotides in which one of the oxygens of the phosphate group is replaced with a sulfur atom.

National Institutes of Health

Papers overview

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2004

Experiments with immunostimulatory unmethylated CpG-containing DNA are usually conducted with nuclease-protected phosphorothioate…

1992

ISIS 1082, a phosphorothioate oligonucleotide targeted to a translation initiation codon of herpes simplex virus type 1 (HSV-1…

1986

Several insecticides were subjected to simulated rainfall after application on octadecylsilanized/trimethylsilanized glass or…

1986

Three aminoalkyl phosphorothioates, WR-2721, WR-3689, and WR-77913, were compared as radioprotectors of RIF-1 tumors irradiated…

1983

Impurities such as O,S,S-trimethyl phosphorodithioate (TMPD) and the S-methyl isomer of malathion (isomalathion) strongly…

1982

The amounts of fensulfothion [0,0-diethyl O-[p-(methylsulfinyl)phenyl] phosphorothioate] and its related sulfide [0,0-diethyl O…

1975

The high antiradiation activity and low toxicity of sodium 3-amino-2-hydroxypropyl hydrogen phosphorothioate (1) suggested the…

1973

ALKALINE phosphatase from Escherichia coli has been reported to be phosphorylated by a phosphate ester substrate1, a particular…

1971

Residues of the insecticide phoxim (phenylglyoxylo nitrile oxime 0,0-diethyl phosphorothioate; Bay 77488) and its oxygen analog…

1964

The available information on the susceptibility of irradiated animals to various drugs and toxic agents indicates that radiation…