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ISIS 2503

Known as: ISIS-2503, ISIS2503 
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the… Expand
National Institutes of Health

Papers overview

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2018
2018
Aloperine (Alo), as a quinolizidine alkaloid extracted from S. alopecuroide, has the positive activities of anti-inflammatory… Expand
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2004
2004
PURPOSE Gemcitabine remains the standard therapy for metastatic pancreatic adenocarcinoma (ACA), but has limited activity. ISIS… Expand
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2003
2003
PURPOSE The purpose of this study was to define the toxicity, pharmacokinetics, and clinical activity of the combination of ISIS… Expand
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2003
2003
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
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2001
2001
BACKGROUND Abnormal expression of Ras proteins frequently is found with oncogenic transformation making ras a promising… Expand
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2001
2001
  • Michael Morse
  • Current opinion in molecular therapeutics
  • 2001
  • Corpus ID: 7918845
ISIS-2503, a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression, is being developed by Isis Pharmaceuticals Inc as… Expand
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2001
2001
The plasma pharmacokinetics and tissue disposition of ISIS 2503 were studied in mice following single and multiple bolus… Expand
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1999
1999
AbstractPurpose. This study examined the pharmacokinetics and tissue distribution of an antisense oligonucleotide ISIS 2503… Expand
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