Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

ISIS 2503

Known as: ISIS-2503, ISIS2503 
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Aloperine (Alo), as a quinolizidine alkaloid extracted from S. alopecuroide, has the positive activities of anti-inflammatory… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Highly Cited
2004
Highly Cited
2004
PURPOSE Gemcitabine remains the standard therapy for metastatic pancreatic adenocarcinoma (ACA), but has limited activity. ISIS… Expand
2004
2004
AbstractPurpose. This study examined the pharmacokinetics and tissue distribution of an antisense oligonucleotide ISIS 2503… Expand
Highly Cited
2003
Highly Cited
2003
PURPOSE The purpose of this study was to define the toxicity, pharmacokinetics, and clinical activity of the combination of ISIS… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
2003
2003
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… Expand
Highly Cited
2001
Highly Cited
2001
Abnormal expression of Ras proteins frequently is found with oncogenic transformation making ras a promising therapeutic target… Expand
2001
2001
  • M. Morse
  • Current opinion in molecular therapeutics
  • 2001
  • Corpus ID: 7918845
ISIS-2503, a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression, is being developed by Isis Pharmaceuticals Inc as… Expand
Highly Cited
2001
Highly Cited
2001
The plasma pharmacokinetics and tissue disposition of ISIS 2503 were studied in mice following single and multiple bolus… Expand