ISIS 2503

Known as: ISIS-2503, ISIS2503 
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2003
012319992003

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
PURPOSE Gemcitabine remains the standard therapy for metastatic pancreatic adenocarcinoma (ACA), but has limited activity. ISIS… (More)
Is this relevant?
2003
2003
PURPOSE The purpose of this study was to define the toxicity, pharmacokinetics, and clinical activity of the combination of ISIS… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
2003
2003
Purpose: The purpose of this study was to define the toxicity, pharmacokinetics, and clinical activity of the combination of ISIS… (More)
  • table 1
  • table 2
  • table 3
  • table 4
  • figure 1
Is this relevant?
2001
2001
ISIS-2503, a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression, is being developed by Isis Pharmaceuticals Inc as… (More)
Is this relevant?
2001
2001
BACKGROUND Abnormal expression of Ras proteins frequently is found with oncogenic transformation making ras a promising… (More)
Is this relevant?
2001
2001
The plasma pharmacokinetics and tissue disposition of ISIS 2503 were studied in mice following single and multiple bolus… (More)
Is this relevant?
1999
1999
Purpose. This study examined the pharmacokinetics and tissue distribution of an antisense oligonucleotide ISIS 2503, formulated… (More)
Is this relevant?