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ISIS 2503

Known as: ISIS-2503, ISIS2503 
A synthetic oligodeoxynucleotide. Functioning as an anti-sense agent, it hybridizes to the translation initiation region of the human mRNA for the… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Phosphorothioate Oligonucleotides
gemcitabine/ISIS 2503

Papers overview

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2003
2003
Gateways to clinical trials.
Gateways to Clinical Trials is a guide to the most recent clinical trials in current literature and congresses. The data in the… 
2001
2001
Technology evaluation: ISIS-2503, Isis Pharmaceuticals.
  • M. Morse
  • Current opinion in molecular therapeutics (Print)
  • 2001
  • Corpus ID: 7918845
ISIS-2503, a 20-mer antisense oligonucleotide that inhibits Ha-Ras expression, is being developed by Isis Pharmaceuticals Inc as… 
Highly Cited
2001
Highly Cited
2001
Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha-ras mRNA in mouse and monkey.
The plasma pharmacokinetics and tissue disposition of ISIS 2503 were studied in mice following single and multiple bolus… 
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