Skip to search formSkip to main contentSkip to account menu

alacepril

Known as: N-(1-(3-(acetylthio)-2-methyl-1-oxopropyl)-L-prolyl)-L-phenylalanine, aracepril 
A long-acting, sulfhydryl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, alacepril is rapidly… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCaptopril

Narrower (1)

DU 1219
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1999
1999
Antiatherosclerotic effect of alacepril, an angiotensin-converting enzyme inhibitor, in monkeys fed a high-cholesterol diet.
We investigated the effects of 6 months' treatment with the angiotensin-converting enzyme (ACE) inhibitor alacepril, given in low… 
1998
1998
Gene expression of endothelin-1 and endothelial-type nitric oxide synthase in cardiovascular tissues of stroke-prone spontaneously hypertensive rats/Izm: effects of the angiotensin-converting enzyme…
We studied target organ-protective effects of aracepril, an angiotensin-converting enzyme inhibitor, and the expression of… 
1994
1994
Mechanistic analysis of renal protection by angiotensin converting enzyme inhibitor in Dahl salt‐sensitive rats
Objective To investigate whether and how renin-angiotensin inhibition attenuates renal injury seen in salt-induced hypertension… 
1989
1989
Antihypertensive mechanism of alacepril. Effects of its metabolites on the peripheral sympathetic nervous system.
To elucidate the antihypertensive mechanisms of alacepril (DU-1219), the drug itself and its metabolites, desacetylalacepril (DU… 
1987
1987
Role of renin-angiotensin and kallikrein-kinin systems on the mechanism of the hypotensive effects of converting enzyme inhibitor, alacepril.
In four patients with essential hypertension and one patient with renovascular hypertension, decreases in blood pressure and… 
1986
1986
Disposition and metabolism of the novel antihypertensive agent alacepril in rats.
Disposition and metabolism of 1-[(S)-3-acetylthio-2-methylpropanoyl]-L-prolyl-L-phenylalanine (alacepril, DU-1219) in rats were… 
1986
1986
Effect of alacepril on renin-angiotensin-aldosterone system and kallikrein-kinin-prostaglandin system in experimental animals.
The effects of 1-[(S)-3-acetylthio-2-methylpropanoyl]-L-prolyl-L-phenylalanine (alacepril, DU-1219), an orally active angiotensin… 
1985
1985
Pharmacokinetics of a new angiotensin I converting enzyme inhibitor (alacepril) after oral dosing in fasting or fed states
The plasma concentration and urinary excretion of a newly developed angiotensin I converting enzyme inhibitor, alacepril (which… 
1985
1985
Antihypertensive activity of alacepril, an orally active angiotensin converting enzyme inhibitor, in renal hypertensive rats and dogs.
Alacepril (1-[(S)-3-acetylthio-2-methylpropanoyl]-L-prolyl-L-phenylalanine, DU-1219) showed a dose related and long lasting… 
1985
1985
Antihypertensive activity of alacepril in spontaneously hypertensive rats and deoxycorticosterone acetate-salt hypertensive rats and dogs.
Antihypertensive activity of alacepril (1-[(S)-3-acetylthio-2-methylpropanoyl]-L-prolyl-L-phenylalanine, DU-1219), an orally… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)