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alacepril

Known as: N-(1-(3-(acetylthio)-2-methyl-1-oxopropyl)-L-prolyl)-L-phenylalanine, aracepril 
A long-acting, sulfhydryl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, alacepril is rapidly… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (3)

Angiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsCaptopril

Narrower (1)

DU 1219
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Screening of Extracts from Red Algae in Jeju for Potentials MarineAngiotensin - I Converting Enzyme (ACE) Inhibitory Activity
Hypertension is a worldwide problem of epidemic proportions, affecting 15-20% of adults. It is the most common serious chronic… 
2002
2002
Effects of the angiotensin‐converting enzyme inhibitor alacepril on exercise capacity and neurohormonal factors in patients with mild‐to‐moderate heart failure
1. Alacepril is a long‐acting, sulphydryl‐containing angiotensin‐converting enzyme inhibitor. Data are limited regarding the… 
1999
1999
Antiatherosclerotic effect of alacepril, an angiotensin-converting enzyme inhibitor, in monkeys fed a high-cholesterol diet.
We investigated the effects of 6 months' treatment with the angiotensin-converting enzyme (ACE) inhibitor alacepril, given in low… 
Review
1997
Review
1997
Long-term infusion of kallikrein attenuates renal injury in Dahl salt-sensitive rats.
1997
1997
Free radical scavenging properties of alacepril metabolites and lisinopril.
Alacepril is an inhibitor of the angiotensin converting enzyme (ACE), and is commonly used as an antihypertensive. In this study… 
1997
1997
Alacepril, an angiotensin-converting enzyme inhibitor, prevents cerebral vasospasm in subarachnoid hemorrhage model in rats.
The effects of angiotensin-converting enzyme (ACE) inhibitors was investigated on the development of cerebral vasospasm and on… 
Highly Cited
1994
Highly Cited
1994
Responses of plasma concentrations of A type natriuretic peptide and B type natriuretic peptide to alacepril, an angiotensin-converting enzyme inhibitor, in patients with congestive heart failure.
BACKGROUND--Plasma concentrations of A type or atrial natriuretic peptide (ANP) and B type or brain natriuretic peptide (BNP) are… 
1994
1994
Role of angiotensin II in extracellular matrix and transforming growth factor-beta 1 expression in hypertensive rats.
1989
1989
Antihypertensive mechanism of alacepril. Effects of its metabolites on the peripheral sympathetic nervous system.
To elucidate the antihypertensive mechanisms of alacepril (DU-1219), the drug itself and its metabolites, desacetylalacepril (DU… 
1985
1985
Pharmacokinetics of a new angiotensin I converting enzyme inhibitor (alacepril) after oral dosing in fasting or fed states
The plasma concentration and urinary excretion of a newly developed angiotensin I converting enzyme inhibitor, alacepril (which… 
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