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aeroplysinin I

Known as: 3,5-dibromo-1,2-dihydroxy-4-methoxy-3,5-cyclohexadiene-1-acetonitrile, aeroplysinin-1, aeroplysinin-I 
 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

AcetonitrilesCyclohexenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug
Organisms lacking external defense mechanisms have developed chemical defense strategies, particularly through the production of… Expand
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2012
2012
The Antiangiogenic Compound Aeroplysinin-1 Induces Apoptosis in Endothelial Cells by Activating the Mitochondrial Pathway
Aeroplysinin-1 is a brominated metabolite extracted from the marine sponge Aplysina aerophoba that has been previously… Expand
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Highly Cited
2006
Highly Cited
2006
Activated Chemical Defense in Aplysina Sponges Revisited
Sponges of the genus Aplysina accumulate brominated isoxazoline alkaloids in concentrations that sometimes exceed 10% of their… Expand
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Highly Cited
2004
Highly Cited
2004
Chemical Defense of Mediterranean Sponges Aplysina cavernicola and Aplysina aerophoba
The Mediterranean sponges Aplysina aerophoba and A. cavernicola accumulate brominated isoxazoline alkaloids including… Expand
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Highly Cited
2002
Highly Cited
2002
Antiangiogenic activity of aeroplysinin-1, a brominated compound isolated from a marine sponge.
(+)-aeroplysinin-1, an antibacterial brominated compound produced by certain sponges, was selected during a blind high-throughput… Expand
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1996
1996
Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba.
Aeroplysinin-1 (1) and the structurally related dienone 2 were cytotoxic to Ehrlich ascites tumor (EAT) cells and HeLa tumor… Expand
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1993
1993
Antibiotic and Cytotoxic Activity of Brominated Compounds from the Marine Sponge Verongia aerophoba
Abstract Analysis of the marine sponge Verongia aerophoba from the Canary Islands afforded eight brominated secondary metabolites… Expand
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1990
1990
Inhibition of intrinsic protein tyrosine kinase activity of EGF-receptor kinase complex from human breast cancer cells by the marine sponge metabolite (+)-aeroplysinin-1.
1. (+)-Aeroplysinin-1, a naturally occurring tyrosine metabolite from the marine sponge Verongia aerophoba, was found to inhibit… Expand
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1989
1989
Cytostatic Activity of Aeroplysinin-1 against Lymphoma and Epithelioma Cells
(±)-Aeroplysinin-1, an optically active 1.2-dihydroarene-1.2-diol. was isolated from the marine sponges Verongia aerophoba… Expand
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1972
1972
Aeroplysinin-1, an antibacterial bromo-compound from the sponge Verongia aerophoba.
Aeroplysinin-1, an antibacterial bromo-compound from the sponge Verongia aerophoba, is the first example of a naturally occurring… Expand
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