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aeroplysinin I

Known as: 3,5-dibromo-1,2-dihydroxy-4-methoxy-3,5-cyclohexadiene-1-acetonitrile, aeroplysinin-1, aeroplysinin-I 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

AcetonitrilesCyclohexenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Aeroplysinin-1, a Sponge-Derived Multi-Targeted Bioactive Marine Drug
Organisms lacking external defense mechanisms have developed chemical defense strategies, particularly through the production of… 
Review
2010
Review
2010
Bioactive natural products from marine sponges and fungal endophytes
This review highlights recent findings of our group on bioactive marine natural products isolated from marine sponges and marine… 
Highly Cited
2006
Highly Cited
2006
Activated Chemical Defense in Aplysina Sponges Revisited
Sponges of the genus Aplysina accumulate brominated isoxazoline alkaloids in concentrations that sometimes exceed 10% of their… 
Highly Cited
2004
Highly Cited
2004
Chemical Defense of Mediterranean Sponges Aplysina cavernicola and Aplysina aerophoba
The Mediterranean sponges Aplysina aerophoba and A. cavernicola accumulate brominated isoxazoline alkaloids including… 
Highly Cited
2003
Highly Cited
2003
Are there activated chemical defenses in sponges of the genus Aplysina from the Caribbean
The Mediterranean sponge Aplysina aerophoba has been proposed to rely on damage- induced activation of chemical defenses against… 
Highly Cited
2002
Highly Cited
2002
Antiangiogenic activity of aeroplysinin‐1, a brominated compound isolated from a marine sponge
(+)‐Aeroplysinin‐1, an antibacterial brominated compound produced by certain sponges, was selected during a blind high‐throughput… 
Highly Cited
1996
Highly Cited
1996
Cytotoxicity and mode of action of aeroplysinin-1 and a related dienonefrom the sponge Aplysina aerophoba.
Aeroplysinin-1 (1) and the structurally related dienone 2 were cytotoxic to Ehrlich ascites tumor (EAT) cells and HeLa tumor… 
Highly Cited
1993
Highly Cited
1993
Antibiotic and Cytotoxic Activity of Brominated Compounds from the Marine Sponge Verongia aerophoba
Abstract Analysis of the marine sponge Verongia aerophoba from the Canary Islands afforded eight brominated secondary metabolites… 
Highly Cited
1990
Highly Cited
1990
Inhibition of intrinsic protein tyrosine kinase activity of EGF-receptor kinase complex from human breast cancer cells by the marine sponge metabolite (+)-aeroplysinin-1.
Highly Cited
1972
Highly Cited
1972
Aeroplysinin-1, an antibacterial bromo-compound from the sponge Verongia aerophoba.
Aeroplysinin-1, an antibacterial bromo-compound from the sponge Verongia aerophoba, is the first example of a naturally occurring… 
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