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aeroplysinin I

Known as: 3,5-dibromo-1,2-dihydroxy-4-methoxy-3,5-cyclohexadiene-1-acetonitrile, aeroplysinin-1, aeroplysinin-I 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

AcetonitrilesCyclohexenes

Papers overview

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2014
2014
Spongean alkaloids protect rat kidney cells against cisplatin-induced cytotoxicity
Nephrotoxicity is the major dose-limiting adverse effect of cisplatin (CisPt) and results from CisPt-induced damage of tubular… 
2014
2014
Marine sponge as a source of antiangiogenic compounds. The case of aeroplysinin-1
The vast majority of the natural compounds that have been previously described as inhibitors of angiogenesis have been isolated… 
2013
2013
An Aeroplysinin-1 Specific Nitrile Hydratase Isolated from the Marine Sponge Aplysina cavernicola
A nitrile hydratase (NHase) that specifically accepts the nitrile aeroplysinin-1 (1) as a substrate and converts it into the… 
Highly Cited
2008
Highly Cited
2008
Bioactive brominated metabolites from the red sea sponge Suberea mollis.
Reinvestigation of the Red Sea sponge Suberea mollis afforded two new bromotyrosine-derived alkaloids, subereamollines A (1) and… 
2007
2007
Antiangiogenic versus cytotoxic activity in analogues of aeroplysinin-1.
Highly Cited
2002
Highly Cited
2002
Antiangiogenic activity of aeroplysinin‐1, a brominated compound isolated from a marine sponge
(+)‐Aeroplysinin‐1, an antibacterial brominated compound produced by certain sponges, was selected during a blind high‐throughput… 
1993
1993
Biotransformation of brominated compounds in the marine spongeVerongia aerophoba — Evidence for an induced chemical defense?
Over the past 20 years marine secondary products have attracted growing interest due to uniqu e chemical features which, for… 
1989
1989
Cytostatic Activity of Aeroplysinin-1 against Lymphoma and Epithelioma Cells
(±)-Aeroplysinin-1, an optically active 1.2-dihydroarene-1.2-diol. was isolated from the marine sponges Verongia aerophoba… 
1985
1985
Conversion of alpha-amino acids and peptides to nitriles and aldehydes by bromoperoxidase.
Pure bromoperoxidase from the marine alga, Penicillus capitatus, converts alpha-amino acids and peptides to the corresponding… 
1984
1984
Inhibitory characteristics of 3,5-dibromo-1-acetoxy-4-oxo-2,5-cyclohexadien-1-acetonitrile, a semisynthetic derivative of aeroplysinin-1 from sponges (Aplysinidae), on Na+ - K+-ATPase.
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