adefovir

Known as: 9-(2-phosphonomethoxyethyl)adenine, Phosphonylmethoxyethyl-a, 9-(2-phophonylmethoxyethyl)adenine 
A nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
A randomized, open-label comparative study of entecavir versus adefovir therapy was performed in subjects with chronic hepatitis… (More)
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Highly Cited
2009
Highly Cited
2009
The 2009 update of the American Association for the Study of Liver Diseases (AASLD) Practice Guidelines for Management of Chronic… (More)
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Highly Cited
2009
Highly Cited
2009
UNLABELLED This study was undertaken to compare the early antiviral activity and viral kinetic profiles of entecavir (ETV) versus… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND & AIMS Adefovir monotherapy is an established treatment modality for lamivudine-experienced patients with chronic… (More)
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Highly Cited
2006
Highly Cited
2006
The reverse-transcriptase inhibitor lamivudine (Zeffix, GlaxoSmithKline) is often used to treat chronic infection with hepatitis… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The incidence and risk factors for adefovir-resistant HBV have not been clearly defined. AIMS To characterize the… (More)
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Highly Cited
2006
Highly Cited
2006
Acyclic nucleotide phosphonates (adefovir, cidofovir, and tenofovir) are eliminated predominantly into the urine, and renal… (More)
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Review
2004
Review
2004
Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people infected worldwide, and 350 million… (More)
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Highly Cited
2000
Highly Cited
2000
The transport of organic anions in proximal convoluted tubules plays an essential role in the active secretion of a variety of… (More)
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Highly Cited
1999
Highly Cited
1999
Nephrotoxicity is the dose-limiting clinical adverse effect of cidofovir and adefovir, two potent antiviral therapeutics. Because… (More)
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