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acetylcholinesterase activity
Known as:
acetyl.beta-methylcholinesterase activity
, acetylcholine acetylhydrolase activity
, acetylthiocholinesterase activity
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Catalysis of the reaction: acetylcholine + H2O = choline + acetate. [EC:3.1.1.7]
National Institutes of Health
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Acetylcholinesterase measurement
Papers overview
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Highly Cited
2011
Highly Cited
2011
Myrtenal inhibits acetylcholinesterase, a known Alzheimer target
Dorothea Kaufmann
,
A. K. Dogra
,
M. Wink
The Journal of pharmacy and pharmacology
2011
Corpus ID: 44962827
Objectives Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of the most general form of dementia…
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Highly Cited
2008
Highly Cited
2008
Effect of donepezil and tacrine on oxidative stress in intracerebral streptozotocin-induced model of dementia in mice.
G. Saxena
,
S. Singh
,
R. Agrawal
,
C. Nath
European Journal of Pharmacology
2008
Corpus ID: 7334421
Highly Cited
2005
Highly Cited
2005
Degree of inhibition of cortical acetylcholinesterase activity and cognitive effects by donepezil treatment in Alzheimer’s disease
N. Bohnen
,
D. Kaufer
,
+9 authors
R. Moore
Journal of Neurology Neurosurgery & Psychiatry
2005
Corpus ID: 19461001
Objectives: To determine in vivo cortical acetylcholinesterase (AChE) activity and cognitive effects in subjects with mild…
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Highly Cited
2002
Highly Cited
2002
Biochemical study on the effects of some Egyptian herbs in alloxan-induced diabetic rats.
Hamdy A. Mansour
,
A. A. Newairy
,
M. Yousef
,
S. A. Sheweita
Toxicology
2002
Corpus ID: 2110957
Highly Cited
2002
Highly Cited
2002
Regional Effects of Donepezil and Rivastigmine on Cortical Acetylcholinesterase Activity in Alzheimer’s Disease
V. Kaasinen
,
K. Någren
,
+5 authors
J. Rinne
Journal of Clinical Psychopharmacology
2002
Corpus ID: 24054480
Donepezil and rivastigmine are acetylcholinesterase (AChE) inhibitors used to improve cholinergic neurotransmission and cognitive…
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Highly Cited
2001
Highly Cited
2001
Effect of donepezil on brain acetylcholinesterase activity in patients with AD measured by PET
H. Shinotoh
,
A. Aotsuka
,
+5 authors
T. Irie
Neurology
2001
Corpus ID: 41718275
Acetylcholinesterase (AChE) activities in the brain of three patients with AD were measured once before and once during donepezil…
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Highly Cited
1999
Highly Cited
1999
Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and progressive supranuclear palsy
H. Shinotoh
,
H. Namba
,
+7 authors
T. Irie
Annals of Neurology
1999
Corpus ID: 6260295
We measured brain acetylcholinesterase activity in 16 patients with Parkinson's disease (PD), 12 patients with progressive…
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Highly Cited
1997
Highly Cited
1997
Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease
M. Iyo
,
H. Namba
,
+6 authors
T. Irie
The Lancet
1997
Corpus ID: 35452889
Highly Cited
1993
Highly Cited
1993
Neurotoxic effect of enteral aluminium.
A. Bilkei-Gorzo
Food and Chemical Toxicology
1993
Corpus ID: 6485631
Highly Cited
1991
Highly Cited
1991
Inhibition of Acetylcholinesterase Activity in Human Brain Tissue and Erythrocytes by Galanthamine, Physostigmine and Tacrine
T. Thomsen
,
B. Kaden
,
+5 authors
H. Kewitz
European journal of clinical chemistry and…
1991
Corpus ID: 11729619
Galanthamine, physostigmine and 9-amino-1,2,3,4-tetrahydroacridine (tacrine) were evaluated as inhibitors of human…
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