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acemetacin

Known as: 1H-indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, carboxymethyl ester, indomethacin carboxymethyl ester 
National Institutes of Health

Related topics

Related topics

19 relations

Narrower (8)

Acemetacin StadaEspledolIndomethacin sodium trihydrateOldan

Broader (2)

Anti-Inflammatory Agents, Non-SteroidalIndomethacin
Indomethacin:MCnc:Pt:Ser/Plas:QnO-desmethylindomethacinPoisoning by antirheumatics [antiphlogistics]Teoremac

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Acemetacin cocrystal structures by powder X-ray diffraction
Acemetacin cocrystals were prepared by melt crystallization and their crystal structures determined by high-resolution powder X… 
2006
2006
An exploratory theoretical elucidation on the peroxyl-radical-scavenging mechanism and structure-activity relationship of nonsteroidal anti-inflammatory drugs.
2005
2005
Pharmacokinetics of Indomethacin, a Metabolite of Acemetacin, Following a Single dose and Multiple doses Administered as Acemetacin Sustained-Release Tablets in Healthy Male Volunteers
The objective of this study was to estimate the pharmacokinetics of the newly developed once-daily acemetacin sustained-release… 
2001
2001
Effect of liposomes on the rate of alkaline hydrolysis of indomethacin and acemetacin.
The anti-inflammatory, analgesic, and antipyretic drugs indomethacin (INDO) and acemetacin (ACE), extensively used for the… 
1993
1993
Acemetacin and indomethacin: differential inhibition of constitutive and inducible cyclo-oxygenases in human gastric mucosa and leucocytes.
Cyclo-oxygenase, a key enzyme in prostaglandin production, is mainly in the constitutive form (COX-1) in gastric mucosa, whereas… 
1991
1991
[Inhibition of thrombocyte function by non-steroidal anti-rheumatic agents: a comparative study between diclofenac, acemetacin, mefenamic acid and ibuprofen].
Non-steroidal antiinflammatory drugs (NSAID) interfere with the synthesis of prostaglandins by inhibiting cyclooxygenase. In… 
1989
1989
[Ranitidine ameliorates acemetacin and indomethacin-induced changes of the gastroduodenal mucosa, without modifying the pharmacokinetic behavior of both antirheumatic drugs].
12 healthy volunteers participated in this double-blind, randomized, cross-over study. All subjects were given indomethacin (50… 
1985
1985
Prostaglandin-related bone resorption in cultured neonatal mouse calvaria: evaluation of biopotency of nonsteroidal anti-inflammatory drugs.
1980
1980
[On the pharmacodynamics of acemetacin (author's transl)].
Pharmacodynamic studies were carried out on (1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetoxy]acetic acid (acemetacin, TV… 
1980
1980
[Controlled double blind study on the effectiveness and adverse effects of acemetacin and indomethacin in the treatment of psoriatic arthritis].
In a controlled double blind study the therapeutic efficacy and tolerability of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3… 
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