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O-desmethylindomethacin

Known as: desmethyl-indomethacin 
National Institutes of Health

Papers overview

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2018
2018
Background and ObjectiveCytochrome P450 (CYP) 2C9 catalyzes the biotransformation of indomethacin to its inactive metabolite O… Expand
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2017
2017
Several lines of evidence have pointed towards the potential therapeutic benefit of NSAIDs in cancer therapy. In this study, we… Expand
2005
2005
A new rapid, selective and sensitive high pressure liquid Chromatographic (HPLC) assay for indomethacin in plasma is described… Expand
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1998
1998
Indomethacin is a widely used nonsteroidal anti-inflammatory drug. We studied the human cytochrome P450 (CYP) isoform responsible… Expand
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1993
1993
Indomethacin is metabolized in humans by O-demethylation, and by acyl glucuronidation to the 1-O-glucuronide. Indomethacin, its… Expand
1982
1982
A rapid and sensitive high-performance liquid chromatography-fluorescence method is described for the quantitative analysis of… Expand