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Background and ObjectiveCytochrome P450 (CYP) 2C9 catalyzes the biotransformation of indomethacin to its inactive metabolite O… Expand Several lines of evidence have pointed towards the potential therapeutic benefit of NSAIDs in cancer therapy. In this study, we… Expand A new rapid, selective and sensitive high pressure liquid Chromatographic (HPLC) assay for indomethacin in plasma is described… Expand Indomethacin is a widely used nonsteroidal anti-inflammatory drug. We studied the human cytochrome P450 (CYP) isoform responsible… Expand Indomethacin is metabolized in humans by O-demethylation, and by acyl glucuronidation to the 1-O-glucuronide. Indomethacin, its… Expand A rapid and sensitive high-performance liquid chromatography-fluorescence method is described for the quantitative analysis of… Expand