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Indomethacin

Known as: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, Indometacinum, Indomethacin [Chemical/Ingredient] 
A synthetic nonsteroidal indole derivative with anti-inflammatory activity and chemopreventive properties. As a nonsteroidal anti-inflammatory drug… Expand
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To study the molecular structure of indomethacin-PVP amorphous solid dispersions and identify any specific… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractPurpose. To measure solid-state features of amorphous molecular dispersions of indomethacin and various molecular weight… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe… Expand
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Highly Cited
2001
Highly Cited
2001
Tryptophan fluorescence wavelength is widely used as a tool to monitor changes in proteins and to make inferences regarding local… Expand
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Highly Cited
1998
Highly Cited
1998
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… Expand
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Review
1998
Review
1998
 
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Highly Cited
1995
Highly Cited
1995
Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely… Expand
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Highly Cited
1993
Highly Cited
1993
In a 6-month, double-blind, placebo-controlled study, 1100 to 150 mg/d indomethacin appeared to protect mild to moderately… Expand
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Highly Cited
1988
Highly Cited
1988
&NA; A method to measure cutaneous hyperalgesia to thermal stimulation in unrestrained animals is described. The testing paradigm… Expand
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Highly Cited
1988
Highly Cited
1988
Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor… Expand
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