Indomethacin

Known as: 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, Indometacinum, Indomethacin [Chemical/Ingredient] 
A synthetic nonsteroidal indole derivative with anti-inflammatory activity and chemopreventive properties. As a nonsteroidal anti-inflammatory drug… (More)
National Institutes of Health

Papers overview

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Review
2018
Review
2018
BACKGROUND Indomethacin is used as standard therapy to close a patent ductus arteriosus (PDA) but is associated with reduced… (More)
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Preliminary research suggests that rectally administered nonsteroidal antiinflammatory drugs may reduce the incidence… (More)
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Highly Cited
1998
Highly Cited
1998
Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… (More)
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Highly Cited
1997
Highly Cited
1997
Indomethacin is a non-steroidal anti-inflammatory drug (NSAID) and cyclooxygenase inhibitor that is frequently used as a research… (More)
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Highly Cited
1997
Highly Cited
1997
Purpose. To study the molecular structure of indomethacin-PVP amorphous solid dispersions and identify any specific interactions… (More)
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Highly Cited
1995
Highly Cited
1995
Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely… (More)
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Highly Cited
1993
Highly Cited
1993
In a 6-month, double-blind, placebo-controlled study, 100 to 150 mg/d indomethacin appeared to protect mild to moderately… (More)
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Highly Cited
1987
Highly Cited
1987
A method to measure cutaneous hyperalgesia to thermal stimulation in unrestrained animals is described. The testing paradigm uses… (More)
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Highly Cited
1987
Highly Cited
1987
The formalin test in mice is a valid and reliable model of nociception and is sensitive for various classes of analgesic drugs… (More)
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Highly Cited
1986
Highly Cited
1986
Sir: Indomethacin (ID) is used as an inhibitor of premature labor since 1974 [1]. This drug can be used for nonsurgical closure… (More)
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