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Preliminary research suggests that rectally administered nonsteroidal antiinflammatory drugs may reduce the incidence… Expand AbstractPurpose. To study the molecular structure of indomethacin-PVP amorphous solid dispersions and identify any specific… Expand BACKGROUND
The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe… Expand Apoptosis in vivo is followed almost inevitably by rapid uptake into adjacent phagocytic cells, a critical process in tissue… Expand Cyclooxygenases 1 and 2 (COX-1 and COX-2) are key enzymes in prostaglandin biosynthesis and the target enzymes for the widely… Expand In a 6-month, double-blind, placebo-controlled study, 1100 to 150 mg/d indomethacin appeared to protect mild to moderately… Expand &NA; A method to measure cutaneous hyperalgesia to thermal stimulation in unrestrained animals is described. The testing paradigm… Expand Endothelin releases prostacyclin and thromboxane A2 from guinea pig or rat isolated lungs and endothelium-derived relaxing factor… Expand Among 3559 newborn infants with birth weight less than 1750 gm, 421 developing a hemodynamically significant patent ductus… Expand The action of these two anti-inflammatory agents provides further support for the suggestion that some of their therapeutic… Expand