Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

abacavir

Known as: 2-Cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-, ABC, {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol 
A nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Genetic polymorphism in the genes encoding the human leukocyte antigen (HLA) molecules enables presentation of a wide range… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
BACKGROUND There are 2 once-daily, fixed-dose-combination, dual-nucleoside analogue tablets: tenofovir 300 mg-emtricitabine 200… Expand
  • figure 1
  • table 1
  • table 1
  • figure 2
  • table 2
Is this relevant?
Highly Cited
2008
Highly Cited
2008
BACKGROUND Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Objective  To improve the definition of the various clinical patterns of patients with drug‐induced cutaneous side‐effects with… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Abacavir therapy is associated with significant drug hypersensitivity in approximately 8% of recipients, with retrospective… Expand
  • table 1
  • table 2
  • figure 1
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Susceptibility to a clinically significant drug hypersensitivity syndrome associated with abacavir use seems to have a strong… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
OBJECTIVE Abacavir, a human immunodeficiency virus-1 (HIV-1) nucleoside-analogue reverse transcriptase inhibitor, causes severe… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Hypersensitivity to abacavir affects about 4% of patients who receive the drug for HIV-1 infection. We did a retrospective, case… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
BACKGROUND The use of abacavir--a potent HIV-1 nucleoside-analogue reverse-transcriptase inhibitor--is complicated by a… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
CONTEXT Peripheral lipoatrophy may complicate antiretroviral therapy of human immunodeficiency virus (HIV) infection, often… Expand
Is this relevant?