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abacavir

Known as: 2-Cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-, ABC, {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol 
A nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune… 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study… 
Highly Cited
2006
Highly Cited
2006
Objective  To improve the definition of the various clinical patterns of patients with drug‐induced cutaneous side‐effects with… 
Highly Cited
2004
Highly Cited
2004
Susceptibility to a clinically significant drug hypersensitivity syndrome associated with abacavir use seems to have a strong… 
Highly Cited
2004
Highly Cited
2004
OBJECTIVE Abacavir, a human immunodeficiency virus-1 (HIV-1) nucleoside-analogue reverse transcriptase inhibitor, causes severe…