Skip to search formSkip to main contentSkip to account menu

abacavir

Known as: 2-Cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-, ABC, {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol 
A nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune… 
National Institutes of Health

Related topics

Related topics

27 relations

Narrower (6)

1592U89EpzicomTriumeqTrizivir
Abacavir:ACnc:Pt:Ser/Plas:QnAbacavir:Susc:Pt:Isolate:OrdQnAbacavir:Susc:Pt:Isolate:OrdQn:GenotypingAcquired Immunodeficiency Syndrome

Broader (5)

Anti-HIV AgentsAntiviral AgentsDeoxyribonucleosidesDideoxynucleosides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
12 Weeks of Daclatasvir in Combination With Sofosbuvir for HIV-HCV Coinfection (ALLY-2 Study): Efficacy and Safety by HIV Combination Antiretroviral Regimens
In human immunodeficiency virus (HIV)-hepatitis C virus-coinfected patients, 12 weeks' daclatasvir + sofosbuvir once-daily… 
Highly Cited
2011
Highly Cited
2011
Hospitalization for severe malnutrition among HIV-infected children starting antiretroviral therapy
Objective:To describe early hospitalization for severe malnutrition in HIV-infected children initiating antiretroviral therapy… 
Highly Cited
2008
Highly Cited
2008
Low Response to Pegylated Interferon plus Ribavirin in HIV-Infected Patients with Chronic Hepatitis C Treated with Abacavir
Background There is little information about the influence of antiretroviral drugs on the antiviral activity of pegylated… 
Highly Cited
2008
Highly Cited
2008
Quantification of seven nucleoside/nucleotide reverse transcriptase inhibitors in human plasma by high-performance liquid chromatography with tandem mass-spectrometry.
Highly Cited
2008
Highly Cited
2008
Increased HIV infection rate among violent deaths: a mortuary study in the Republic of Congo
There is no evidence about an association between violent deaths and HIV in Africa. We report the results of a study performed in… 
Highly Cited
2005
Highly Cited
2005
KP-1212/1461, a nucleoside designed for the treatment of HIV by viral mutagenesis.
Highly Cited
2003
Highly Cited
2003
Clinically relevant interpretation of genotype for resistance to abacavir
Objective: To develop a stepwise methodology for the development and validation of clinically relevant genotypic score for… 
Highly Cited
2002
Highly Cited
2002
Comparison of dual nucleoside-analogue reverse-transcriptase inhibitor regimens with and without nelfinavir in children with HIV-1 who have not previously been treated: the PENTA 5 randomised trial
Highly Cited
2002
Highly Cited
2002
Response to lamivudine-zidovudine plus abacavir twice daily in antiretroviral-naive, incarcerated patients with HIV infection taking directly observed treatment.
Prison inmates with human immunodeficiency virus (HIV) infection can be difficult to treat because of the complexity and… 
Highly Cited
1998
Highly Cited
1998
A dose‐ranging study to evaluate the safety and efficacy of abacavir alone or in combination with zidovudine and lamivudine in antiretroviral treatment‐naive subjects
Objective:To compare antiretroviral efficacy, safety and tolerance of three dosing regimens of the novel nucleoside reverse… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)