Zoxazolamine

Known as: 2-Benzoxazolamine, 5-chloro-, Zoxazolamine [Chemical/Ingredient] 
A uricosuric and muscle relaxant. Zoxazolamine acts centrally as a muscle relaxant, but the mechanism of its action is not understood.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1956-2017
051019562016

Papers overview

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2007
2007
Our previous microarray expression analysis of the long-lived Little mice (Ghrhr(lit/lit)) showed a concerted up-regulation of… (More)
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Highly Cited
2001
Highly Cited
2001
Hepatic hydroxylation is an essential step in the metabolism and excretion of bile acids and is necessary to avoid pathologic… (More)
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Highly Cited
2001
Highly Cited
2001
Identification and characterization of the pregnane X receptor (PXR) as a key regulator of cytochrome P450 3A (CYP3A) gene… (More)
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2001
2001
The alcoholic extract of fresh leaves of the plant Eclipta alba (Ea), previously reported for is hepatoprotective activity was… (More)
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Highly Cited
2000
Highly Cited
2000
Organisms encounter a wide range of foreign compounds—or ‘xenobiotics’—with potentially harmful consequences. The cytochrome P450… (More)
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2000
2000
We previously characterized 1-ethyl-2-benzimidazolinone (1-EBIO), as well as the clinically useful benzoxazoles, chlorzoxazone… (More)
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1996
1996
Cytochrome P450 1A2 (CYP1A2) is a predominantly hepatic enzyme known to be important in the metabolism of numerous foreign… (More)
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1992
1992
Zoxazolamine is in the centrally-acting muscle relaxant class of drugs, which reportedly act by decreasing CNS interneuronal… (More)
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Highly Cited
1985
Highly Cited
1985
Piperine, a major active component of black and long peppers, has been reported to enhance drug bioavailability. The present… (More)
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1982
1982
The metabolism of zoxazolamine to 6-hydroxyzoxazolamine by liver microsomes from neonatal rats is stimulated severalfold by the… (More)
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