Zinc Fingers

Known as: Finger, Zinc, Motif, Zinc Finger, Fingers, Zinc 
Motifs in DNA- and RNA-binding proteins whose amino acids are folded into a single structural unit around a zinc atom. In the classic zinc finger… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Reverse genetics in model organisms such as Drosophila melanogaster, Arabidopsis thaliana, zebrafish and rats, efficient genome… (More)
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Highly Cited
2007
Highly Cited
2007
Achieving the full potential of zinc-finger nucleases (ZFNs) for genome engineering in human cells requires their efficient… (More)
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Highly Cited
2003
Highly Cited
2003
Gene targeting—the process of gene replacement by homologous recombination—is a very useful but typically inefficient technique… (More)
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Highly Cited
2002
Highly Cited
2002
We have identified a novel zinc finger-containing transcription factor, called Osterix (Osx), that is specifically expressed in… (More)
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Highly Cited
2002
Highly Cited
2002
Zinc-finger nucleases (ZFNs) are hybrids between a nonspecific DNA-cleavage domain and a DNA-binding domain composed of Cys(2)His… (More)
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Review
2001
Review
2001
Zinc finger proteins are among the most abundant proteins in eukaryotic genomes. Their functions are extraordinarily diverse and… (More)
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Highly Cited
1996
Highly Cited
1996
A long-term goal in the field of restriction-modification enzymes has been to generate restriction endonucleases with novel… (More)
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Highly Cited
1995
Highly Cited
1995
The vegetative and reproductive (flowering) phases of Arabidopsis development are clearly separated. The onset of flowering is… (More)
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Highly Cited
1991
Highly Cited
1991
The zinc finger DNA-binding motif occurs in many proteins that regulate eukaryotic gene expression. The crystal structure of a… (More)
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Highly Cited
1990
Highly Cited
1990
We have isolated a series of genomic and cDNA clones mapping within the boundaries of constitutional and tumor deletions that… (More)
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