ZEB2 wt Allele

Known as: KIAA0569, ZFX1B, ZFHX1B 
Human ZEB2 wild-type allele is located in the vicinity of 2q22 and is approximately 132 kb in length. This allele, which encodes zinc finger E-box… (More)
National Institutes of Health

Related topics

Related topics

9 relations
2q22Homo sapiensTranscriptional RegulationTranscriptional Repression
(More)

Broader (1)

ZEB2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels.
Aberrant DNA methylation and microRNA expression play important roles in the pathogenesis of pancreatic cancer. While… (More)
  • figure 1
  • table 1
  • table 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2009
Highly Cited
2009
SIP1 protein protects cells from DNA damage-induced apoptosis and has independent prognostic value in bladder cancer.
The epithelial-mesenchymal transition (EMT) contributes to cancer metastasis. Two ZEB family members, ZEB1 and ZEB2(SIP1… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta.
Epithelial-mesenchymal transition (EMT), a crucial event in cancer progression and embryonic development, is induced by… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
miR-200b mediates post-transcriptional repression of ZFHX1B.
MicroRNAs have important functions during animal development and homeostasis through post-transcriptional regulation of their… (More)
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Regulation of vimentin by SIP1 in human epithelial breast tumor cells
The expression of Smad interacting protein-1 (SIP1; ZEB2) and the de novo expression of vimentin are frequently involved in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.
A critical event in the pathogenesis of invasive and metastatic cancer is E-cadherin loss of function. Renal clear cell carcinoma… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.
Epithelial-mesenchymal transition (EMT) is important in embryonic development and tumorigenesis. Smad-interacting protein 1 (SIP1… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.
Epithelial-mesenchymal transition (EMT) involving down-regulation of E-cadherin is thought to play a fundamental role during… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.
Transcriptional downregulation of E-cadherin appears to be an important event in the progression of various epithelial tumors… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease
Hirschsprung disease (HSCR) is sometimes associated with a set of characteristics including mental retardation, microcephaly, and… (More)
  • figure 1
  • figure 2
Is this relevant?