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ZEB2 wt Allele
Known as:
KIAA0569
, ZFX1B
, ZFHX1B
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Human ZEB2 wild-type allele is located in the vicinity of 2q22 and is approximately 132 kb in length. This allele, which encodes zinc finger E-box…
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National Institutes of Health
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Related topics
Related topics
9 relations
2q22
Homo sapiens
Transcriptional Regulation
Transcriptional Repression
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Broader (1)
ZEB2 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
TGF-β drives epithelial-mesenchymal transition through δEF1-mediated downregulation of ESRP
K. Horiguchi
,
K. Sakamoto
,
+8 authors
M. Saitoh
Oncogene
2011
Corpus ID: 6530620
Epithelial-mesenchymal transition (EMT) is a crucial event in wound healing, tissue repair and cancer progression in adult…
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Highly Cited
2010
Highly Cited
2010
Pancreatic cancers epigenetically silence SIP1 and hypomethylate and overexpress miR-200a/200b in association with elevated circulating miR-200a and miR-200b levels.
Ang Li
,
N. Omura
,
+5 authors
M. Goggins
Cancer Research
2010
Corpus ID: 2417562
Aberrant DNA methylation and microRNA expression play important roles in the pathogenesis of pancreatic cancer. While…
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Highly Cited
2008
Highly Cited
2008
Genome‐wide microRNA expression profiling in renal cell carcinoma: significant down‐regulation of miR‐141 and miR‐200c
C. Nakada
,
K. Matsuura
,
+10 authors
M. Moriyama
Journal of Pathology
2008
Corpus ID: 22490375
We investigated expression profiles of microRNA (miRNA) in renal cell carcinoma [clear cell carcinomas (CCC) and chromophobe…
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Highly Cited
2007
Highly Cited
2007
miR-200b mediates post-transcriptional repression of ZFHX1B.
N. R. Christoffersen
,
A. Silahtaroglu
,
U. A. Orom
,
S. Kauppinen
,
A. Lund
RNA: A publication of the RNA Society
2007
Corpus ID: 11354998
MicroRNAs have important functions during animal development and homeostasis through post-transcriptional regulation of their…
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Highly Cited
2006
Highly Cited
2006
Hypoxia-inducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B.
B. Krishnamachary
,
D. Zagzag
,
+4 authors
G. Semenza
Cancer Research
2006
Corpus ID: 26773856
A critical event in the pathogenesis of invasive and metastatic cancer is E-cadherin loss of function. Renal clear cell carcinoma…
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Highly Cited
2003
Highly Cited
2003
Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.
T. van de Putte
,
Mitsuji Maruhashi
,
+4 authors
Y. Higashi
American Journal of Human Genetics
2003
Corpus ID: 24891686
Recently, mutations in ZFHX1B, the gene that encodes Smad-interacting protein-1 (SIP1), were found to be implicated in the…
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Highly Cited
2002
Highly Cited
2002
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer.
E. Rosivatz
,
I. Becker
,
+5 authors
K. Becker
American Journal of Pathology
2002
Corpus ID: 461744
Highly Cited
2001
Highly Cited
2001
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion.
J. Comijn
,
G. Berx
,
+6 authors
F. van Roy
Molecules and Cells
2001
Corpus ID: 35528338
Highly Cited
2001
Highly Cited
2001
Loss-of-function mutations in SIP1 Smad interacting protein 1 result in a syndromic Hirschsprung disease.
V. Cacheux
,
F. Dastot‐Le Moal
,
+6 authors
M. Goossens
Human Molecular Genetics
2001
Corpus ID: 14411802
Hirschsprung disease (HD) has been described in association with microcephaly, mental retardation and characteristic facial…
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Highly Cited
2001
Highly Cited
2001
Mutations in SIP1, encoding Smad interacting protein-1, cause a form of Hirschsprung disease
N. Wakamatsu
,
Yasukazu Yamada
,
+10 authors
M. Nagaya
Nature Genetics
2001
Corpus ID: 39070888
Hirschsprung disease (HSCR) is sometimes associated with a set of characteristics including mental retardation, microcephaly, and…
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