FAQ

ZEB2 gene

Known as: ZINC FINGER E BOX-BINDING HOMEOBOX 2, zinc finger E-box binding homeobox 2, KIAA0569 
This gene is involved in regulation of transcription.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
05020012017

Related topics

Related topics

7 relations
Homo sapiensTranscriptional RegulationTranscriptional Repressiondna binding
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Narrower (1)

ZEB2 wt Allele

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
ZEB2 gene
dna binding
Homo sapiens
protein protein interaction
Transcriptional Regulation
nervous system development

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Upregulated MALAT-1 contributes to bladder cancer cell migration by inducing epithelial-to-mesenchymal transition.
Recent studies reveal that long non-coding RNAs (lncRNAs) have been shown to have important regulatory roles in cancer biology… (More)
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Highly Cited
2011
Highly Cited
2011
p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
p53 suppresses tumor progression and metastasis. Epithelial-mesenchymal transition (EMT) is a key process in tumor progression… (More)
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Highly Cited
2011
Highly Cited
2011
Coordinated epigenetic repression of the miR-200 family and miR-205 in invasive bladder cancer.
MicroRNAs (miRNA) are small noncoding RNAs commonly deregulated in cancer. The miR-200 family (miR-200a, -200b, -200c, -141 and… (More)
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Highly Cited
2011
Highly Cited
2011
Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma.
Endometrial carcinosarcomas (ECSs) undergo a true epithelial-mesenchymal transition (EMT). The molecular determinants of the EMT… (More)
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Highly Cited
2011
Highly Cited
2011
Over-expression of FoxM1 leads to epithelial-mesenchymal transition and cancer stem cell phenotype in pancreatic cancer cells.
FoxM1 is known to play important role in the development and progression of many malignancies including pancreatic cancer… (More)
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Highly Cited
2010
Highly Cited
2010
miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.
Throughout most of pregnancy, uterine quiescence is maintained by increased progesterone receptor (PR) transcriptional activity… (More)
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Highly Cited
2008
Highly Cited
2008
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2.
Cancer progression has similarities with the process of epithelial-to-mesenchymal transition (EMT) found during embryonic… (More)
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Highly Cited
2008
Highly Cited
2008
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.
MicroRNAs are small non-coding RNA molecules that can regulate gene expression by interacting with multiple mRNAs and inducing… (More)
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Highly Cited
2008
Highly Cited
2008
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Epithelial to mesenchymal transition (EMT) facilitates tissue remodelling during embryonic development and is viewed as an… (More)
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Highly Cited
2003
Highly Cited
2003
Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.
Recently, mutations in ZFHX1B, the gene that encodes Smad-interacting protein-1 (SIP1), were found to be implicated in the… (More)
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