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ZAP70 wt Allele

Known as: Zeta-Chain (TCR) Associated Protein Kinase 70kDa wt Allele, SRK, ZAP-70 
Human ZAP70 wild-type allele is located within 2q12 and is approximately 26 kb in length. This allele, which encodes ZAP70 protein, plays a role in… 
National Institutes of Health

Related topics

Related topics

18 relations
2q12Cell Differentiation processCell ProliferationChronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region Gene

Broader (1)

ZAP70 gene

Papers overview

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2018
2018
Serum Immunoglobulin Paraprotein in Patients with Chronic Lymphocytic Leukemia
Background: Chronic Lymphocytic Leukemia (CLL) is the most common chronic lympho-proliferative disorder. This study was done to… 
2016
2016
Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis
2013
2013
IN SITU IMMUNE RESPONSE EVALUATION VIA IMMUNOHISTOCHEMISTRY IN SKIN BIOPSIES FROM PATIENTS AFFECTED
Introduction: The in situ immune response in skin biopsies from patients affected by autoimmune skin blistering diseases (ABD) is… 
Review
2012
Review
2012
The Biological Relevance of ZAP-70 in CLL
Initially, CLL was considered as a homogeneous disease caused by the accumulation of functionally incompetent B lymphocytes… 
2011
2011
SALT AND PEPPER STAINING PATTERNS FOR LAT, ZAP-70 AND MUM-1 IN A VASCULITIC BULLOUS ALLERGIC DRUG ERUPTION WZÓR BARWIENIA SÓL I PIEPRZ DLA LAT, ZAP-70 I MUM-1 W NACZYNIOWYCH PĘCHERZACH REAKCJI…
Background. The term bullous drug eruption refers to clinicall y adverse drug reactions that result in fluid-fille d blisters or… 
2008
2008
[The transcription levels of linker for activation of T cell and its upstream regulatory factors in T cells of asthmatic patients].
OBJECTIVE To examine the mRNA expression of the linker for activation of T cell (LAT) and its upstream regulatory factors (Syk… 
2006
2006
CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38− counter-parts
CD38 + chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38… 
2005
2005
Marcadores de prognóstico na leucemia linfocítica crônica
Chronic lymphocytic leukemia is characterized by a variable clinical course that cannot be predicted accurately by clinical… 
1998
1998
Trichosanthin inhibits T cell activation by interfering with the recruitment of ZAP-70 to CD3 ζ chain
Plant protein Trichosanthin (Tk) has been shown in our previous experiments to suppress antigenic response of T cells. Here we… 
1995
1995
Le déficit en tyrosine kinase ZAP-70 : un modèle de déficit immunitaire héréditaire pour l'analyse de l'activation et de la différenciation des lymphocytes T
L'identification des bases molécu­ laires de certains déficits immuni­ taires héréditaires rares a permis de mettre en évidence…