ZAP70 wt Allele

Known as: Zeta-Chain (TCR) Associated Protein Kinase 70kDa wt Allele, SRK, ZAP-70 
Human ZAP70 wild-type allele is located within 2q12 and is approximately 26 kb in length. This allele, which encodes ZAP70 protein, plays a role in… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
0102019922018

Papers overview

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Highly Cited
2008
Highly Cited
2008
Leukemia-cell expression of ZAP-70, CD38, or unmutated immunoglobulin heavy chain variable region genes (U-IGHV) each is… (More)
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Highly Cited
2007
Highly Cited
2007
The 2 subsets of chronic lymphocytic leukemia (CLL), of worse or better prognosis, likely derive from pre-GC unmutated B cells… (More)
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Highly Cited
2007
Highly Cited
2007
Expression of ZAP-70 is an important negative prognostic factor in chronic lymphocytic leukemia (CLL). This protein tyrosine… (More)
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Highly Cited
2007
Highly Cited
2007
HIV efficiently spreads in lymphocytes, likely through virological synapses (VSs). These cell-cell junctions share some… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Chronic lymphocytic leukaemia (CLL) is a heterogeneous disease; many patients never need treatment, whereas some have… (More)
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Highly Cited
2003
Highly Cited
2003
The presence or absence of somatic mutations in the expressed immunoglobulin heavy chain variable regions (IgVH) of chronic… (More)
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Highly Cited
2003
Highly Cited
2003
B-cell chronic lymphocytic leukemia (B-CLL) is a heterogenous disease with a highly variable clinical course. Recent studies have… (More)
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Highly Cited
1996
Highly Cited
1996
Two families of tyrosine kinases, the Src and Syk families, are required for T-cell receptor activation. While the Src kinases… (More)
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Highly Cited
1995
Highly Cited
1995
DURING thymic development, T cells that can recognize foreign antigen in association with self major histocompatibility complex… (More)
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Highly Cited
1992
Highly Cited
1992
Protein-tyrosine kinases (PTKs) play an integral role in T cell activation. Stimulation of the T cell antigen receptor (TCR… (More)
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