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ZAP70 gene

Known as: ZAP70, STD, SRK 
This gene is involved in tyrosine phosphorylation and T-cell activation.
National Institutes of Health

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Related topics

15 relations
Cell Differentiation processCell ProliferationChronic Lymphocytic Leukemia with Unmutated Immunoglobulin Heavy Chain Variable-Region GeneHomo sapiens

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ZAP70 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Dexamethasone induces rapid tyrosine-phosphorylation of ZAP-70 in Jurkat cells
2004
2004
Interaction of human MUC1 and beta-catenin is regulated by Lck and ZAP-70 in activated Jurkat T cells.
2004
2004
T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk.
Engagement of the T-cell receptor (TCR) results in the activation of Lck/Fyn and ZAP-70/Syk tyrosine kinases. Lck-mediated… 
2000
2000
Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.
The protein tyrosine kinase ZAP-70 is implicated in the early steps of the T-cell antigen receptor (TCR) signaling. Binding of… 
Highly Cited
1999
Highly Cited
1999
Characterization of S tester lines in Brassica oleracea: polymorphism of restriction fragment length of SLG homologues and isoelectric points of S-locus glycoproteins
Abstract Forty three S tester lines of Brassica oleracea were characterized using DNA and protein gel-blotting analyses. DNA gel… 
1999
1999
Interaction between CD45-AP and Protein-tyrosine Kinases Involved in T Cell Receptor Signaling*
CD45-AP associates specifically with CD45, a protein-tyrosine phosphatase essential for antigen receptor-mediated signal… 
1998
1998
Increased Zap-70 association with CD3zeta in CD4 T cells from old mice.
Aging diminishes the amount of phosphotyrosine in the CD3zeta chains of resting and activated mouse CD4 T cells by about… 
1998
1998
Identification of the Fc epsilonRI-activated tyrosine kinases Lyn, Syk, and Zap-70 in human basophils.
BACKGROUND In human blood basophils, cross-linking the high-affinity IgE receptor Fc epsilonRI with multivalent antigen activates… 
1996
1996
Beta1 integrin-mediated activation of focal adhesion kinase and its association with Fyn and Zap-70 in human NK cells.
Adhesive interactions mediated by cell surface receptors have been shown to induce signal transduction pathways that regulate… 
1994
1994
Lymphocyte antigen receptor activation of a focal adhesion kinase-related tyrosine kinase substrate.
One of the earliest responses of T and B lymphocytes to stimulation through their antigen receptors is the activation of protein… 
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