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Xenograft type of graft
Known as:
Xenotransplantation
, grafts heteroplastic
, xenografting
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The transfer of cells, tissues, or organs from a donor into a recipient of another species.
National Institutes of Health
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Related topics
Related topics
7 relations
Blood supply aspects
Microbiological
Process of secretion
Xenograft procedure
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Ferroptosis as a p53-mediated activity during tumour suppression
Le Jiang
,
N. Kon
,
+5 authors
W. Gu
Nature
2015
Corpus ID: 205243244
Although p53-mediated cell-cycle arrest, senescence and apoptosis serve as critical barriers to cancer development, emerging…
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Highly Cited
2007
Highly Cited
2007
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
A. Karnoub
,
A. Dash
,
+7 authors
R. Weinberg
Nature
2007
Corpus ID: 4317561
Mesenchymal stem cells have been recently described to localize to breast carcinomas, where they integrate into the tumour…
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Highly Cited
2006
Highly Cited
2006
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo.
O. Farokhzad
,
Jianjun Cheng
,
+5 authors
R. Langer
Proceedings of the National Academy of Sciences…
2006
Corpus ID: 10463758
Targeted uptake of therapeutic nanoparticles in a cell-, tissue-, or disease-specific manner represents a potentially powerful…
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Highly Cited
2004
Highly Cited
2004
Identification of human brain tumour initiating cells
Sheila K. Singh
,
C. Hawkins
,
+7 authors
P. Dirks
Nature
2004
Corpus ID: 4430962
The cancer stem cell (CSC) hypothesis suggests that neoplastic clones are maintained exclusively by a rare fraction of cells with…
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Highly Cited
2003
Highly Cited
2003
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic…
D. Mendel
,
A. Laird
,
+20 authors
J. Cherrington
Clinical Cancer Research
2003
Corpus ID: 1801681
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising…
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Highly Cited
2000
Highly Cited
2000
Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
R. Clynes
,
Terri L. Towers
,
L. Presta
,
J. Ravetch
Nature Network Boston
2000
Corpus ID: 20629632
Inhibitory receptors have been proposed to modulate the in vivo cytotoxic response against tumor targets for both spontaneous and…
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Highly Cited
1999
Highly Cited
1999
Safety and antitumor activity of recombinant soluble Apo2 ligand.
A. Ashkenazi
,
R. Pai
,
+15 authors
R. Schwall
Journal of Clinical Investigation
1999
Corpus ID: 21339379
TNF and Fas ligand induce apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their…
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Highly Cited
1997
Highly Cited
1997
Interstitial pH and pO2 gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
G. Helmlinger
,
F. Yuan
,
M. Dellian
,
R. Jain
Nature Network Boston
1997
Corpus ID: 12815062
The partial pressure of oxygen (pO2) and pH play critical roles in tumor biology and therapy. We report here the first combined…
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Highly Cited
1995
Highly Cited
1995
Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size.
Fan Yuan
,
M. Dellian
,
+4 authors
R. Jain
Cancer Research
1995
Corpus ID: 15701574
Molecular size is one of the key determinants of transvascular transport of therapeutic agents in tumors. However, there are no…
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Highly Cited
1989
Highly Cited
1989
Monoclonal antibody-mediated tumor regression by induction of apoptosis.
B. Trauth
,
C. Klas
,
+5 authors
P. Krammer
Science
1989
Corpus ID: 25836407
To characterize cell surface molecules involved in control of growth of malignant lymphocytes, monoclonal antibodies were raised…
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