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Xenograft procedure
Known as:
Xenotransplantation
, Heterologous Transplantation
, Xenograft Transplantation
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Transplantation between animals of different species.
National Institutes of Health
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Related topics
Related topics
7 relations
Educational aspects
Xenograft type of graft
legislation & jurisprudence
nursing therapy
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Broader (2)
Organ Transplantation
Transplantation
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
S. Pyonteck
,
L. Akkari
,
+17 authors
J. Joyce
Nature Network Boston
2013
Corpus ID: 9849614
Glioblastoma multiforme (GBM) comprises several molecular subtypes, including proneural GBM. Most therapeutic approaches…
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Highly Cited
2009
Highly Cited
2009
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
Teresa A. Soucy
,
Peter G. Smith
,
+32 authors
S. Langston
Nature
2009
Corpus ID: 41289859
The clinical development of an inhibitor of cellular proteasome function suggests that compounds targeting other components of…
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Highly Cited
2008
Highly Cited
2008
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
H. Christofk
,
M. V. Heiden
,
+6 authors
L. Cantley
Nature
2008
Corpus ID: 16111842
Many tumour cells have elevated rates of glucose uptake but reduced rates of oxidative phosphorylation. This persistence of high…
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Highly Cited
2008
Highly Cited
2008
Identification and expansion of the tumorigenic lung cancer stem cell population
A. Eramo
,
F. Lotti
,
+7 authors
R. Maria
Cell Death and Differentiation
2008
Corpus ID: 2484961
Lung carcinoma is often incurable and remains the leading cancer killer in both men and women. Recent evidence indicates that…
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Highly Cited
2007
Highly Cited
2007
A perivascular niche for brain tumor stem cells.
C. Calabrese
,
H. Poppleton
,
+13 authors
R. Gilbertson
Cancer Cell
2007
Corpus ID: 11725201
Highly Cited
2005
Highly Cited
2005
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
V. Gorgoulis
,
L. Vassiliou
,
+12 authors
T. Halazonetis
Nature
2005
Corpus ID: 4426996
DNA damage checkpoint genes, such as p53, are frequently mutated in human cancer, but the selective pressure for their…
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Highly Cited
2004
Highly Cited
2004
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
L. Vassilev
,
B. Vu
,
+9 authors
E. A. Liu
Science
2004
Corpus ID: 16132757
MDM2 binds the p53 tumor suppressor protein with high affinity and negatively modulates its transcriptional activity and…
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Highly Cited
2003
Highly Cited
2003
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic…
D. Mendel
,
A. Laird
,
+20 authors
J. Cherrington
Clinical Cancer Research
2003
Corpus ID: 1801681
One challenging aspect in the clinical development of molecularly targeted therapies, which represent a new and promising…
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Highly Cited
1998
Highly Cited
1998
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model.
W. Arap
,
R. Pasqualini
,
E. Ruoslahti
Science
1998
Corpus ID: 28152718
In vivo selection of phage display libraries was used to isolate peptides that home specifically to tumor blood vessels. When…
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Highly Cited
1997
Highly Cited
1997
PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer
Jing Li
,
Clifford Yen
,
+14 authors
R. Parsons
Science
1997
Corpus ID: 23093929
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN…
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