XRCC5 wt Allele

Known as: X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) wt Allele, Ku80, NFIV 
Human XRCC5 wild-type allele is located within 2q35 and is approximately 99 kb in length. This allele, which encodes X-ray repair cross-complementing… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1989-2018
051019892018

Papers overview

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Highly Cited
2012
Highly Cited
2012
The ubiquitination cascade has a key role in the assembly of repair and signaling proteins at sites of double-strand DNA breaks… (More)
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2011
2011
PURPOSE Radiotherapy plays an integral role in the treatment of head and neck squamous cell carcinoma (HNSCC). Although proteins… (More)
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2009
2009
PURPOSE To investigate the association between dose-related parameters and polymorphisms in DNA DSB repair genes XRCC3 (c.-1843A… (More)
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2008
2008
The Ku70/Ku80 heterodimer, or Ku, is the central component of the nonhomologous end joining (NHEJ) pathway of double strand break… (More)
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2008
2008
Ku plays a key role in multiple nuclear processes, e.g., DNA double-strand break (DSB) repair. The regulation mechanism of the… (More)
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2008
2008
BRCA1 is the first susceptibility gene to be linked to breast and ovarian cancers. Although mounting evidence has indicated that… (More)
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2003
2003
Chromosomal breaks are repaired by homologous recombination (HR) or non-homologous end joining (NHEJ) mechanisms. The Ku70/Ku80… (More)
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2003
2003
Cell death linked to oxidative DNA damage has been implicated in acute pancreatitis. The severe DNA damage, which is beyond the… (More)
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Highly Cited
1997
Highly Cited
1997
We recently have shown that mice deficient for the 86-kDa component (Ku80) of the DNA-dependent protein kinase exhibit growth… (More)
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1989
1989
Employing an exonuclease III protection assay we detected a protein in crude HeLa nuclear extracts binding, with apparent… (More)
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