Skip to search formSkip to main contentSkip to account menu

XRCC5 wt Allele

Known as: X-ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) wt Allele, Ku80, NFIV 
Human XRCC5 wild-type allele is located within 2q35 and is approximately 99 kb in length. This allele, which encodes X-ray repair cross-complementing… 
National Institutes of Health

Related topics

Related topics

12 relations
2q35Chromosomal translocationDNA RepairHomo sapiens

Broader (1)

XRCC5 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Dose response and adaptive response of non-homologous end joining repair genes and proteins in resting human peripheral blood mononuclear cells exposed to γ radiation.
Ionising radiation induces single-strand breaks, double-strand breaks (DSB) and base damages in human cell. DSBs are the most… 
2012
2012
Oxidative stress status in metastatic breast cancer patients receiving palliative chemotherapy and its impact on survival rates
Antineoplastic agents are known to induce the production of free radicals leading to cell damage. These adverse effects may fuel… 
2008
2008
Ku80 as a Novel Receptor for Thymosin β4 That Mediates Its Intracellular Activity Different from G-actin Sequestering*
Our data demonstrate that increased intracellular expression of thymosin β4(Tβ4) is necessary and sufficient to induce… 
2006
2006
Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine.
2005
2005
Ku86 preserves chromatin integrity in cells adapted to high NaCl.
Cells adapted to high NaCl have many DNA breaks both in cell culture and in the renal inner medulla in vivo; yet they survive… 
2004
2004
Coexposure to benzo[a]pyrene plus UVA induced DNA double strand breaks: visualization of Ku assembly in the nucleus having DNA lesions.
2000
2000
An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria.
Mammalian mitochondrial DNA end-binding activity is nearly indistinguishable from that of nuclear Ku. This observation led to the… 
1999
1999
Role of DNA-PK subunits in radiosensitization by hyperthermia.
Thermal radiosensitization is thought to result from inhibition of repair of radiation-induced DNA damage, DNA double-strand… 
1991
1991
Identification of Nuclear Factor IV/Ku autoantigen in a human 2D‐gel protein database Modification of the large subunit depends on cellular proliferation
1990
1990
The autoantigen Ku is indistinguishable from NF IV, a protein forming multimeric protein-DNA complexes
We have isolated a cDNA encoding the 84-kD subunit of NFIV. Tryptic peptide sequences were identified within the coding sequences… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)