XRCC3 gene

Known as: X-ray repair complementing defective repair in Chinese hamster cells 3, XRCC3, X-RAY REPAIR, COMPLEMENTING DEFECTIVE, IN CHINESE HAMSTER, 3 
This gene plays a role in recombination and in the maintenance of DNA integrity.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2017
0204019952017

Papers overview

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2008
2008
OBJECTIVESXRCC2 and XRCC3 are key components of the homologous recombination (HR) machinery that repairs DNA double-strand breaks… (More)
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Highly Cited
2003
Highly Cited
2003
Mammalian cells are constantly exposed to a wide variety of genotoxic agents from both endogenous and exogenous sources. Genetic… (More)
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Highly Cited
2003
Highly Cited
2003
Tobacco smoking and occupational exposures are the main known risk factors for bladder cancer, causing direct and indirect damage… (More)
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2003
Highly Cited
2003
DNA repair has an essential role in protecting the genome from damage by endogenous and environmental agents. Polymorphisms in… (More)
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Highly Cited
2002
Highly Cited
2002
We performed genetic association studies in a population-based breast cancer case-control study analysing polymorphisms in genes… (More)
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Highly Cited
2002
Highly Cited
2002
XRCC3 is a RAD51 paralog that functions in the repair of DNA double-strand breaks (DSBs) by homologous recombination (HR). XRCC3… (More)
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Highly Cited
2001
Highly Cited
2001
Individuals differ widely in their ability to repair DNA damage, and DNA-repair deficiency may be involved in modulating cancer… (More)
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Highly Cited
2000
Highly Cited
2000
Growth and development are dependent on the faithful duplication of cells. Duplication requires accurate genome replication, the… (More)
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Highly Cited
1998
Highly Cited
1998
The phenotypically similar hamster mutants irs1 and irs1SF exhibit high spontaneous chromosome instability and broad-spectrum… (More)
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Highly Cited
1995
Highly Cited
1995
The mutagen-sensitive CHO line irs1SF was previously isolated on the basis of hypersensitivity to ionizing radiation and was… (More)
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