Whole genome sequencing

Known as: Complete genome sequencing, Whole genome sequence, Single cell genome sequencing 
Whole genome sequencing (also known as WGS, full genome sequencing, complete genome sequencing, or entire genome sequencing) is a laboratory process… (More)
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Highly Cited
2016
Highly Cited
2016
The MetaCyc database (MetaCyc.org) is a freely accessible comprehensive database describing metabolic pathways and enzymes from… (More)
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Highly Cited
2015
Highly Cited
2015
We compared whole-exome sequencing (WES) and whole-genome sequencing (WGS) in six unrelated individuals. In the regions targeted… (More)
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Highly Cited
2015
Highly Cited
2015
Tumors often contain multiple subpopulations of cancerous cells defined by distinct somatic mutations. We describe a new method… (More)
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Highly Cited
2014
Highly Cited
2014
UNLABELLED The multiplex capability and high yield of current day DNA-sequencing instruments has made bacterial whole genome… (More)
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Highly Cited
2013
Highly Cited
2013
SUMMARY Limitations of genome sequencing techniques have led to dozens of assembly algorithms, none of which is perfect. A number… (More)
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Highly Cited
2012
Highly Cited
2012
MOTIVATION The sequencing of tumors and their matched normals is frequently used to study the genetic composition of cancer… (More)
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Highly Cited
2011
Highly Cited
2011
Epidemics of drug-resistant bacteria emerge worldwide, even as resistant strains frequently have reduced fitness compared to… (More)
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Highly Cited
2010
Highly Cited
2010
Plague is a pandemic human invasive disease caused by the bacterial agent Yersinia pestis. We here report a comparison of 17… (More)
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Highly Cited
2009
Highly Cited
2009
The human genome project has been recently complemented by whole-genome assessment sequence of 32 mammals and 24 nonmammalian… (More)
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Highly Cited
2008
Highly Cited
2008
Forward genetic mutational studies, adaptive evolution, and phenotypic screening are powerful tools for creating new variant… (More)
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