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Werner Syndrome

Known as: syndromes werner's, PROGERIA, OF ADULT, Adult Progeria 
An inherited disorder marked by rapid aging that begins in early adolescence. Patients may be shorter than average, and have health problems such as… 
National Institutes of Health

Related topics

Related topics

33 relations
Autosomal recessive inheritanceCataractChromosomes, Human, Pair 8Diabetes Mellitus

Broader (3)

Hereditary DiseasesPremature aging syndromeSyndrome

Narrower (2)

Lipomatosis, Multiple SymmetricalPeptide growth factors deficiency

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Primary Study Endpoint Analysis for NRG Oncology/RTOG 0813 Trial of Stereotactic Body Radiation Therapy (SBRT) for Centrally Located Non-Small Cell Lung Cancer (NSCLC)
Highly Cited
2006
Highly Cited
2006
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase β
Genome instability is a characteristic of cancer and aging, and is a hallmark of the premature aging disorder Werner syndrome (WS… 
Highly Cited
2002
Highly Cited
2002
Werner syndrome diploid fibroblasts are sensitive to 4‐nitroquinoline‐N‐oxide and 8‐methoxypsoralen: implications for the disease phenotype
The clinical phenotype of Werner Syndrome (WRN) includes features reminiscent of accelerated aging and an increased incidence of… 
Highly Cited
2001
Highly Cited
2001
p53 Modulates the Exonuclease Activity of Werner Syndrome Protein*
Werner syndrome (WS) is characterized by the early onset of symptoms of premature aging, cancer, and genomic instability. The… 
Highly Cited
2000
Highly Cited
2000
Role of foreign-object damage on thresholds for high-cycle fatigue in Ti-6Al-4V
The increasing incidence of military aircraft engine failures that can be traced to high-cycle fatigue (HCF) has prompted a… 
Highly Cited
1998
Highly Cited
1998
Replication focus-forming activity 1 and the Werner syndrome gene product
The initiation of DNA replication involves a minimum of four factors: a specific DNA sequence (origin), an initiator protein… 
Highly Cited
1997
Highly Cited
1997
Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.
Werner syndrome (WS) is an autosomal recessive disease with a complex phenotype that is suggestive of accelerated aging. WS is… 
Highly Cited
1992
Highly Cited
1992
A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts.
Highly Cited
1992
Highly Cited
1992
Nucleotide sequence analysis of human hypoxanthine phosphoribosyltransferase (HPRT) gene deletions.
Highly Cited
1976
Highly Cited
1976
Chromatid exchanges in ataxia telangiectasia, Bloom syndrome, Werner syndrome, and xeroderrna pigmentosum
The frequency of BrdU-induced sister chromatid exchanges (SCE) in cultured lymphocytes from patients with ataxia telangiectasia… 
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