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Premature aging syndrome
Known as:
Aging, Premature
, syndrome premature aging
, premature ageing
(More)
Changes in the organism associated with senescence, occurring at an accelerated rate.
Topic mentions per year
Topic mentions per year
1937-2018
0
50
100
150
1937
2017
Related topics
Related topics
11 relations
Broader (1)
Aging
In Blood
Microbiological
chemically induced
nursing therapy
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Narrower (4)
Penttinen-Aula syndrome
Progeria
WOLFRAM SYNDROME 2
Werner Syndrome
Related mentions per year
Related mentions per year
1936-2018
1940
1960
1980
2000
2020
Premature aging syndrome
Aging
radiotherapeutic
prevention & control
Microbiological
nursing therapy
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Muscle wasting in myotonic dystrophies: a model of premature aging
Alba Judith Mateos-Aierdi
,
María Goicoechea
,
+4 authors
Adolfo López de Munáin
Front. Aging Neurosci.
2015
Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive…
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Highly Cited
2009
Highly Cited
2009
TAp63 prevents premature aging by promoting adult stem cell maintenance.
Xiaohua Su
,
Maryline Paris
,
+9 authors
E. R. Rodrı́guez - Flores
Cell stem cell
2009
The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the…
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Highly Cited
2006
Highly Cited
2006
Lamin A-dependent nuclear defects in human aging.
Paola Scaffidi
,
Tom Misteli
Science
2006
Mutations in the nuclear structural protein lamin A cause the premature aging syndrome Hutchinson-Gilford progeria (HGPS…
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Highly Cited
2006
Highly Cited
2006
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
Dale K Shumaker
,
Thomas Dechat
,
+9 authors
Robert D. Goldman
Proceedings of the National Academy of Sciences…
2006
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant lamin A (LADelta50). Nuclei in…
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Highly Cited
2006
Highly Cited
2006
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Ruben Agrelo
,
W D Cheng
,
+12 authors
Manel Esteller
Proceedings of the National Academy of Sciences…
2006
Werner syndrome (WS) is an inherited disorder characterized by premature onset of aging, genomic instability, and increased…
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Highly Cited
2005
Highly Cited
2005
Genomic instability in laminopathy-based premature aging
Baohua Liu
,
Jianming Wang
,
+18 authors
Zhongjun Zhou
Nature Medicine
2005
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin…
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Highly Cited
2005
Highly Cited
2005
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
Paola Scaffidi
,
Tom Misteli
Nature Medicine
2005
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in…
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Highly Cited
2003
Highly Cited
2003
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Maria E Eriksson
,
W. Ted Brown
,
+14 authors
Francis S. Collins
Nature
2003
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature…
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Highly Cited
1997
Highly Cited
1997
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
David A. Sinclair
,
Leonard P. Guarente
Cell
1997
Although many cellular and organismal changes have been described in aging individuals, a precise, molecular cause of aging has…
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Highly Cited
1996
Highly Cited
1996
Positional cloning of the Werner's syndrome gene.
C E Yu
,
J. Oshima
,
+10 authors
Gerard D. Schellenberg
Science
1996
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a…
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