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Premature aging syndrome

Known as: Premature Aging, Aging, Premature, syndrome premature aging 
Changes in the organism associated with senescence, occurring at an accelerated rate.
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

Aging
In BloodMicrobiologicalchemically inducednursing therapy
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Narrower (5)

Penttinen-Aula syndromePremature Aging Syndrome, Okamoto TypeProgeriaWOLFRAM SYNDROME 2
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Physiological roles of mitochondrial reactive oxygen species.
Historically, mitochondrial reactive oxygen species (mROS) were thought to exclusively cause cellular damage and lack a… Expand
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Review
2010
Review
2010
The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors.
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The understanding of the risk factors for… Expand
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Highly Cited
2006
Highly Cited
2006
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant lamin A (LADelta50). Nuclei in… Expand
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Highly Cited
2006
Highly Cited
2006
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock.
Mice deficient in the circadian transcription factor BMAL1 (brain and muscle ARNT-like protein) have impaired circadian behavior… Expand
Highly Cited
2005
Highly Cited
2005
Genomic instability in laminopathy-based premature aging
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin… Expand
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Highly Cited
2005
Highly Cited
2005
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in… Expand
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Highly Cited
2004
Highly Cited
2004
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
The ‘ataxia telangiectasia mutated’ (Atm) gene maintains genomic stability by activating a key cell-cycle checkpoint in response… Expand
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Highly Cited
2003
Highly Cited
2003
Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature… Expand
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Highly Cited
1997
Highly Cited
1997
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
Although many cellular and organismal changes have been described in aging individuals, a precise, molecular cause of aging has… Expand
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Highly Cited
1996
Highly Cited
1996
Positional Cloning of the Werner's Syndrome Gene
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a… Expand
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