Premature aging syndrome

Known as: Aging, Premature, syndrome premature aging, premature ageing 
Changes in the organism associated with senescence, occurring at an accelerated rate.

Topic mentions per year

Topic mentions per year

1937-2018
05010015019372017

Papers overview

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Review
2015
Review
2015
Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive… (More)
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Highly Cited
2009
Highly Cited
2009
The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the… (More)
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Highly Cited
2006
Highly Cited
2006
Mutations in the nuclear structural protein lamin A cause the premature aging syndrome Hutchinson-Gilford progeria (HGPS… (More)
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Highly Cited
2006
Highly Cited
2006
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant lamin A (LADelta50). Nuclei in… (More)
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Highly Cited
2006
Highly Cited
2006
Werner syndrome (WS) is an inherited disorder characterized by premature onset of aging, genomic instability, and increased… (More)
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Highly Cited
2005
Highly Cited
2005
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin… (More)
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Highly Cited
2005
Highly Cited
2005
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in… (More)
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Highly Cited
2003
Highly Cited
2003
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature… (More)
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Highly Cited
1997
Highly Cited
1997
Although many cellular and organismal changes have been described in aging individuals, a precise, molecular cause of aging has… (More)
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Highly Cited
1996
Highly Cited
1996
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a… (More)
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