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Premature aging syndrome

Known as: Premature Aging, Aging, Premature, syndrome premature aging 
Changes in the organism associated with senescence, occurring at an accelerated rate.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Historically, mitochondrial reactive oxygen species (mROS) were thought to exclusively cause cellular damage and lack a… Expand
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Review
2010
Review
2010
Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. The understanding of the risk factors for… Expand
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Highly Cited
2006
Highly Cited
2006
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant lamin A (LADelta50). Nuclei in… Expand
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Highly Cited
2006
Highly Cited
2006
Mice deficient in the circadian transcription factor BMAL1 (brain and muscle ARNT-like protein) have impaired circadian behavior… Expand
Highly Cited
2005
Highly Cited
2005
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin… Expand
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Highly Cited
2005
Highly Cited
2005
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in… Expand
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Highly Cited
2004
Highly Cited
2004
The ‘ataxia telangiectasia mutated’ (Atm) gene maintains genomic stability by activating a key cell-cycle checkpoint in response… Expand
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Highly Cited
2003
Highly Cited
2003
Hutchinson–Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature… Expand
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Highly Cited
1997
Highly Cited
1997
Although many cellular and organismal changes have been described in aging individuals, a precise, molecular cause of aging has… Expand
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Highly Cited
1996
Highly Cited
1996
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a… Expand