FAQ

Premature aging syndrome

Known as: Aging, Premature, syndrome premature aging, premature ageing 
Changes in the organism associated with senescence, occurring at an accelerated rate.

Topic mentions per year

Topic mentions per year

1937-2018
05010015019372017

Related topics

Related topics

11 relations

Broader (1)

Aging
In BloodMicrobiologicalchemically inducednursing therapy
(More)

Narrower (4)

Penttinen-Aula syndromeProgeriaWOLFRAM SYNDROME 2Werner Syndrome

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Premature aging syndrome
Aging
radiotherapeutic
prevention & control
Microbiological
nursing therapy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Muscle wasting in myotonic dystrophies: a model of premature aging
Myotonic dystrophy type 1 (DM1 or Steinert's disease) and type 2 (DM2) are multisystem disorders of genetic origin. Progressive… (More)
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Highly Cited
2009
Highly Cited
2009
TAp63 prevents premature aging by promoting adult stem cell maintenance.
The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the… (More)
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Highly Cited
2006
Highly Cited
2006
Lamin A-dependent nuclear defects in human aging.
Mutations in the nuclear structural protein lamin A cause the premature aging syndrome Hutchinson-Gilford progeria (HGPS… (More)
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Highly Cited
2006
Highly Cited
2006
Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
The premature aging disease Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant lamin A (LADelta50). Nuclei in… (More)
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Highly Cited
2006
Highly Cited
2006
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Werner syndrome (WS) is an inherited disorder characterized by premature onset of aging, genomic instability, and increased… (More)
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Highly Cited
2005
Highly Cited
2005
Genomic instability in laminopathy-based premature aging
Premature aging syndromes often result from mutations in nuclear proteins involved in the maintenance of genomic integrity. Lamin… (More)
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Highly Cited
2005
Highly Cited
2005
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in… (More)
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Highly Cited
2003
Highly Cited
2003
Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by features reminiscent of marked premature… (More)
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Highly Cited
1997
Highly Cited
1997
Extrachromosomal rDNA Circles— A Cause of Aging in Yeast
Although many cellular and organismal changes have been described in aging individuals, a precise, molecular cause of aging has… (More)
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Highly Cited
1996
Highly Cited
1996
Positional cloning of the Werner's syndrome gene.
Werner's syndrome (WS) is an inherited disease with clinical symptoms resembling premature aging. Early susceptibility to a… (More)
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