Skip to search formSkip to main contentSkip to account menu

WNT5A Protein, human

Known as: WNT5A Gene Product, hWnt-5A protein, human, WNT5A Protein 
Encoded by human WNT5A Gene (WNT Family), 365-aa 41-kDa (precursor) WNT5A Protein, a cysteine-rich secreted glycoprotein growth factor, is involved… 
National Institutes of Health

Related topics

Related topics

11 relations
Cell Fate ControlCell ProliferationEmbryonic DevelopmentIntercellular Communication Process

Broader (1)

Wnt-5a Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase
Wnt5a is a representative ligand that activates the β-catenin-independent pathway in Wnt signaling. Although it has been reported… 
Review
2009
Review
2009
Ror‐family receptor tyrosine kinases in noncanonical Wnt signaling: Their implications in developmental morphogenesis and human diseases
The Ror‐family receptor tyrosine kinases (RTKs) play crucial roles in the development of various organs and tissues. In mammals… 
Highly Cited
2009
Highly Cited
2009
WNT5A mutations in patients with autosomal dominant Robinow syndrome
Robinow syndrome is a skeletal dysplasia with both autosomal dominant and autosomal recessive inheritance patterns. It is… 
Highly Cited
2009
Highly Cited
2009
Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells
Backgroundβ-catenin mutations that constitutively activate the canonical Wnt signaling have been observed in a subset of… 
Highly Cited
2008
Highly Cited
2008
Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase
Wnts are secreted glycoproteins that control vital biological processes, including embryogenesis, organogenesis and tumorigenesis… 
Highly Cited
2008
Highly Cited
2008
WNT5A Expression Increases during Melanoma Progression and Correlates with Outcome
Purpose: Wnt ligands play a major role in development and are important in cancer. Expression microarray analysis correlates one… 
Highly Cited
2007
Highly Cited
2007
The Wnt5A/Protein Kinase C Pathway Mediates Motility in Melanoma Cells via the Inhibition of Metastasis Suppressors and Initiation of an Epithelial to Mesenchymal Transition*
We have shown that Wnt5A increases the motility of melanoma cells. To explore cellular pathways involving Wnt5A, we compared gain… 
Highly Cited
2006
Highly Cited
2006
Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration
The receptor tyrosine kinase Ror2 plays important roles in developmental morphogenesis. It has recently been shown that Ror2… 
Highly Cited
2003
Highly Cited
2003
The receptor tyrosine kinase Ror2 is involved in non‐canonical Wnt5a/JNK signalling pathway
Background: Ror2 is an orphan receptor, belonging to the Ror family of receptor tyrosine kinases. Although Ror2 has been shown to… 
Highly Cited
2003
Highly Cited
2003
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
Wnt proteins, regulators of development in many organisms, bind to seven transmembrane–spanning (7TMS) receptors called frizzleds… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)