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Hepatocellular carcinoma (HCC) is one of the most lethal malignancies in the world. Several signaling pathways, including the… Expand Rationale We have previously shown increased expression of the Frizzled-8 receptor of the Wingless/integrase-1 (WNT) signalling… Expand The purpose of this study was to investigate whether gastroduodenal reflux can play a role in the pathogenesis of hypopharyngeal… Expand OBJECTIVES
Aberrant androgen receptor (AR) signaling functions are implicated in prostate cancer (PCa) pathogenesis. Here, we… Expand Objectives Effects of insulin-like growth factor 1 (IGF1), fibroblast growth factor 2 (FGF2) and bone morphogenetic protein 2… Expand Wingless/integrase-1 (WNT) signaling is a key pathway regulating various aspects of embryonic development; however it also… Expand AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism; its activity is regulated by a plethora of… Expand Based on the capacity of mesenchymal stem cells (MSC) to differentiate into multiple cell types in vitro and in vivo, MCS may be… Expand Abstract: Chondrocyte maturation during endochondral bone formation is regulated by a number of signals that either promote or… Expand We have adapted the avian leukosis virus RCAS (replication-competent avian sarcoma-leukosis virus LTR splice acceptor)-mediated… Expand