WFDC2 gene

Known as: dJ461P17.6, EDDM4, WAP Four-Disulfide Core Domain 2 Gene 
This gene plays a putative role in epithelial host defense.
National Institutes of Health

Papers overview

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2014
2014
Selective overexpression of Human epididymal secretory protein E4 (HE4) points to a role in ovarian cancer tumorigenesis but… (More)
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2013
2013
OBJECTIVE The quality of first surgery is one of the most important prognostic factors in ovarian cancer patients. Pre-surgical… (More)
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Highly Cited
2011
Highly Cited
2011
The aim of this study is to evaluate a new tumour marker, HE4, in comparison with CA 125 and the Risk of Ovarian Malignancy… (More)
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2011
2011
This study was designed to determine whether serum HE4 is an independent prognostic factor in ovarian cancer patients. We… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES The CA125 tumor marker is used to help predict the presence of ovarian cancer in patients with an adnexal mass… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The Whey Acidic Protein domain is an evolutionarily conserved motif found in a number of proteins, the best studied of… (More)
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Highly Cited
2005
Highly Cited
2005
OBJECTIVES The molecular pathogenesis of ovarian serous tumors of low malignant potential (S-LMP) is not well understood… (More)
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Highly Cited
2005
Highly Cited
2005
Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human… (More)
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Highly Cited
2003
Highly Cited
2003
The WFDC2 (HE4) gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low… (More)
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Highly Cited
2002
Highly Cited
2002
The whey acidic protein (WAP) domain is a conserved motif, containing eight cysteines found in a characteristic 4-disulphide core… (More)
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