WFDC2 wt Allele

Known as: dJ461P17.6, EDDM4, HE4 
Human WFDC2 wild-type allele is located within 20q12-q13.2 and is approximately 12 kb in length. This allele, which encodes WAP four-disulfide core… (More)
National Institutes of Health

Papers overview

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2012
2012
OBJECTIVE The purpose of this study was to establish normal ranges for human epididymis protein 4 (HE4) serum levels in healthy… (More)
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Prior studies suggest that combining the Symptom Index (SI) with a serum HE4 test or a CA125 test may improve… (More)
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Highly Cited
2009
Highly Cited
2009
Human epididymis protein 4 (HE4) has recently been described as a new marker for the early diagnosis of ovarian cancer (OC). The… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVES The CA125 tumor marker is used to help predict the presence of ovarian cancer in patients with an adnexal mass… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Tumor markers with increased sensitivity and specificity for endometrial cancer are needed to help monitor response to… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The Whey Acidic Protein domain is an evolutionarily conserved motif found in a number of proteins, the best studied of… (More)
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Highly Cited
2005
Highly Cited
2005
Among the genes most commonly identified in gene expression profiles of epithelial ovarian carcinomas (EOC) is the gene for human… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND When ovarian carcinoma is diagnosed in stage I, up to 90% of patients can be cured with surgery and currently… (More)
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Highly Cited
2003
Highly Cited
2003
The WFDC2 (HE4) gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low… (More)
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Highly Cited
2002
Highly Cited
2002
The whey acidic protein (WAP) domain is a conserved motif, containing eight cysteines found in a characteristic 4-disulphide core… (More)
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