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Vincamine

Known as: Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-, Vincamine [Chemical/Ingredient] 
A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (13)

11-bromovincamineCerebroxineDevincanPervincamine

Broader (3)

Antihypertensive AgentsVasodilator AgentsVinca Alkaloids
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
2012
Highly Cited
2012
Flunarizine
SummarySynopsisFlunarizine is a class IV calcium antagonist with a pharmacological profile which suggests its therapeutic… 
2010
2010
Alpneumines A-H, new anti-melanogenic indole alkaloids from Alstonia pneumatophora.
2010
2010
Separation of vinca alkaloid enantiomers by capillary electrophoresis applying cyclodextrin derivatives and characterization of cyclodextrin complexes by nuclear magnetic resonance spectroscopy.
Review
2005
Review
2005
Eburnamine derivatives and the brain
The Apocynaceae plant family contains a great number of so called eburnamine–vincamine alkaloids. Quite a few of these alkaloids… 
2000
2000
In Vitro-In Vivo Correlation and Comparative Bioavailablity of Vincamine in Prolonged-Release Preparations
Developing an in vitro dissolution test that gives good correlation with in vivo data for a particular drug product is an… 
1991
1991
Effects of several cerebroprotective drugs on NMDA channel function: evaluation using Xenopus oocytes and [3H]MK-801 binding.
1988
1988
Comparison of the effects of vinpocetine, vincamine, and nicergoline on the normal and hypoxia‐damaged learning process in spontaneously hypertensive rats
Vinpocetine (Cavinton®), vincamine, and nicergoline (Sermion®) were evaluated for the ability to protect cognitive function of… 
Highly Cited
1986
Highly Cited
1986
Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles.
Hexyl cyanoacrylate nanoparticles loaded with vincamine as a drug model were prepared. Disposition kinetics and oral… 
1985
1985
Alteration of enzymes in ageing human fibroblasts in culture. III. Modification of superoxide dismutase as an environmental and reversible process
1984
1984
Effect of a new eburnamine derivative, RU 24722, on the turnover of monoamines in mouse brain: selective and reversible decrease of noradrenaline.
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