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Vincamine
Known as:
Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-
, Vincamine [Chemical/Ingredient]
A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in…
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National Institutes of Health
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Related topics
Related topics
23 relations
Narrower (13)
11-bromovincamine
Cerebroxine
Devincan
Pervincamine
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Broader (3)
Antihypertensive Agents
Vasodilator Agents
Vinca Alkaloids
In Blood
agonists
analogs & derivatives
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
An update on vinpocetine: New discoveries and clinical implications
Yishuai Zhang
,
Jian-Dong Li
,
Chen Yan
European journal of pharmacology
2018
Corpus ID: 46768104
Highly Cited
2011
Highly Cited
2011
Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
B. Özçelik
,
M. Kartal
,
I. Orhan
Pharmaceutical biology
2011
Corpus ID: 207525858
Objective: Some natural products consisting of the alkaloids yohimbine and vincamine (indole-type), scopolamine and atropine…
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Highly Cited
2010
Highly Cited
2010
Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
K. Jeon
,
Xiangbin Xu
,
+7 authors
Chen Yan
Proceedings of the National Academy of Sciences
2010
Corpus ID: 5655767
Inflammation is a hallmark of many diseases, such as atherosclerosis, chronic obstructive pulmonary disease, arthritis…
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Highly Cited
2005
Highly Cited
2005
[11C]Vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies
B. Gulyás
,
C. Halldin
,
+7 authors
L. Farde
Journal of the Neurological Sciences
2005
Corpus ID: 1386044
Highly Cited
1997
Highly Cited
1997
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
J. Jakubík
,
L. Bačáková
,
E. El-Fakahany
,
S. Tuček
Molecular pharmacology
1997
Corpus ID: 1325996
It is well known that allosteric modulators of muscarinic acetylcholine receptors can both diminish and increase the affinity of…
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Highly Cited
1996
Highly Cited
1996
Therapeutic efficacy of vincamine in dementia.
P. K. Fischhof
,
R. Möslinger-Gehmayr
,
W. Herrmann
,
A. Friedmann
,
D. Russmann
Neuropsychobiology
1996
Corpus ID: 25557143
This trial was performed to investigate the therapeutic efficacy of vincamine in the treatment of primary degenerative and…
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Review
1987
Review
1987
Buflomedil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in peripheral and cerebral vascular diseases.
S. Clissold
,
S. Lynch
,
E. Sorkin
Drugs
1987
Corpus ID: 195697627
Buflomedil hydrochloride is a vasoactive drug with a variety of pharmacodynamic properties. Importantly, it seems to improve…
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Highly Cited
1987
Highly Cited
1987
Vinpocetine enhances retrieval of a step-through passive avoidance response in rats
V. Denoble
Pharmacology Biochemistry and Behavior
1987
Corpus ID: 42830613
Highly Cited
1986
Highly Cited
1986
Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles.
P. Maincent
,
R. Le Verge
,
P. Sado
,
P. Couvreur
,
J. Devissaguet
Journal of pharmaceutical sciences
1986
Corpus ID: 22107818
Hexyl cyanoacrylate nanoparticles loaded with vincamine as a drug model were prepared. Disposition kinetics and oral…
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Highly Cited
1986
Highly Cited
1986
Vinpocetine: Nootropic effects on scopolamine-induced and hypoxia-induced retrieval deficits of a step-through passive avoidance response in rats
V. Denoble
,
Susan J. Repetti
,
Laura W. Gelpke
,
L. Wood
,
K. Keim
Pharmacology Biochemistry and Behavior
1986
Corpus ID: 32835688
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