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Vincamine

Known as: Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-, Vincamine [Chemical/Ingredient] 
A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in… Expand
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (13)

11-bromovincamineCerebroxineDevincanPervincamine
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Broader (3)

Antihypertensive AgentsVasodilator AgentsVinca Alkaloids
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
Objective: Some natural products consisting of the alkaloids yohimbine and vincamine (indole-type), scopolamine and atropine… Expand
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2011
2011
Vincamine-producing endophytic fungus isolated from Vinca minor.
Vinca minor is a plant containing the alkaloid vincamine, which is used in the pharmaceutical industry as a cerebral stimulant… Expand
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Highly Cited
2010
Highly Cited
2010
Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
Inflammation is a hallmark of many diseases, such as atherosclerosis, chronic obstructive pulmonary disease, arthritis… Expand
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Highly Cited
2008
Highly Cited
2008
Smart stability-indicating spectrophotometric methods for determination of binary mixtures without prior separation.
Ratio subtraction and isosbestic point methods are 2 innovating spectrophotometric methods used to determine vincamine in the… Expand
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Highly Cited
1997
Highly Cited
1997
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
It is well known that allosteric modulators of muscarinic acetylcholine receptors can both diminish and increase the affinity of… Expand
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Highly Cited
1996
Highly Cited
1996
Therapeutic efficacy of vincamine in dementia.
This trial was performed to investigate the therapeutic efficacy of vincamine in the treatment of primary degenerative and… Expand
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1996
1996
Vincamine and vincanol are potent blockers of voltage-gated Na+ channels.
The effects of three vinca derivatives on [3H]batrachotoxin binding in rat cortical synaptosomes, on the inhibition of whole-cell… Expand
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1990
1990
Effects of aging and vincamine derivatives on pericapillary microenvironment: stereological characterization of the cerebral capillary network
Changes in the pericapillary microenvironment of adult (18-month-old) and senescent (27 1/2-month-old) Fischer-344 rats treated… Expand
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1987
1987
Reactions with indole derivatives-LV. : An enantiodivergent route to both vincamine enantiomers
The enantioselective synthesis of the tetracyclic lactam 4 is reported which by enantiodivergent techniques is converted into… Expand
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Highly Cited
1986
Highly Cited
1986
Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles.
Hexyl cyanoacrylate nanoparticles loaded with vincamine as a drug model were prepared. Disposition kinetics and oral… Expand
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