Skip to search formSkip to main contentSkip to account menu

Vincamine

Known as: Eburnamenine-14-carboxylic acid, 14,15-dihydro-14-hydroxy-, methyl ester, (3alpha,14beta,16alpha)-, Vincamine [Chemical/Ingredient] 
A major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (13)

11-bromovincamineCerebroxineDevincanPervincamine

Broader (3)

Antihypertensive AgentsVasodilator AgentsVinca Alkaloids
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
An update on vinpocetine: New discoveries and clinical implications
Highly Cited
2011
Highly Cited
2011
Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
Objective: Some natural products consisting of the alkaloids yohimbine and vincamine (indole-type), scopolamine and atropine… 
Highly Cited
2010
Highly Cited
2010
Vinpocetine inhibits NF-κB–dependent inflammation via an IKK-dependent but PDE-independent mechanism
Inflammation is a hallmark of many diseases, such as atherosclerosis, chronic obstructive pulmonary disease, arthritis… 
Highly Cited
2005
Highly Cited
2005
[11C]Vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies
Highly Cited
1997
Highly Cited
1997
Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors.
It is well known that allosteric modulators of muscarinic acetylcholine receptors can both diminish and increase the affinity of… 
Highly Cited
1996
Highly Cited
1996
Therapeutic efficacy of vincamine in dementia.
This trial was performed to investigate the therapeutic efficacy of vincamine in the treatment of primary degenerative and… 
Review
1987
Review
1987
Buflomedil. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in peripheral and cerebral vascular diseases.
Buflomedil hydrochloride is a vasoactive drug with a variety of pharmacodynamic properties. Importantly, it seems to improve… 
Highly Cited
1987
Highly Cited
1987
Vinpocetine enhances retrieval of a step-through passive avoidance response in rats
  • V. Denoble
  • Pharmacology Biochemistry and Behavior
  • 1987
  • Corpus ID: 42830613
Highly Cited
1986
Highly Cited
1986
Disposition kinetics and oral bioavailability of vincamine-loaded polyalkyl cyanoacrylate nanoparticles.
Hexyl cyanoacrylate nanoparticles loaded with vincamine as a drug model were prepared. Disposition kinetics and oral… 
Highly Cited
1986
Highly Cited
1986
Vinpocetine: Nootropic effects on scopolamine-induced and hypoxia-induced retrieval deficits of a step-through passive avoidance response in rats
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License