Vinca Alkaloids

Known as: Vinca Alkaloids [Chemical/Ingredient], vinca alkaloid, Vinca Alkaloid Compound 
A type of drug that blocks cell growth by stopping mitosis (cell division). Vinca alkaloids interfere with microtubules (cellular structures that… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Neurotoxic anticancer drugs, such as platinum-based anticancer drugs, taxanes, vinca alkaloids, and proteasome/angiogenesis… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Several recent trials have shown a significant overall survival (OS) benefit from postoperative cisplatin-based… (More)
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Review
2004
Review
2004
Highly dynamic mitotic-spindle microtubules are among the most successful targets for anticancer therapy. Microtubule-targeted… (More)
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Highly Cited
2001
Highly Cited
2001
The two second-generation Vinca alkaloids, vinorelbine and vinflunine, affect microtubule dynamics very differently from… (More)
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Highly Cited
2001
Highly Cited
2001
Vinca alkaloids are used extensively in the treatment of childhood acute lymphoblastic leukemia (ALL) and despite their… (More)
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Highly Cited
1993
Highly Cited
1993
We have investigated the blood flow modifying effects of the vinca alkaloids, vincristine and vinblastine in the murine carcinoma… (More)
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Review
1992
Review
1992
Vinca alkaloids, including vinblastine, vincristine, vindesine and vinorelbine, are widely used antineoplastic drugs, either as… (More)
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Highly Cited
1991
Highly Cited
1991
We have used a structure-activity approach to investigate whether the Vinca alkaloids inhibit cell proliferation primarily by… (More)
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Highly Cited
1979
Highly Cited
1979
Starting with an established line of human leukemic lympho blasts (CCRF-CEM), we have developed sublines with varying degrees of… (More)
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Review
1963
Review
1963
A phytochemical investigation of the plant Vinca ro@eaLinn. has demonstrated that a number of alkaloidal substances can be… (More)
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