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Veratridine

Known as: Cevane-3,4,12,14,16,17,20-heptol, 4,9-epoxy-, 3-(3,4-dimethoxybenzoate), (3beta,4alpha,16beta)-, Veratridine [Chemical/Ingredient] 
A benzoate-cevane found in VERATRUM and Schoenocaulon. It activates SODIUM CHANNELS to stay open longer than normal.
National Institutes of Health

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In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Broader (1)

Veratrum Alkaloids

Papers overview

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2009
2009
The effect of some drugs with purported antianoxic effect on veratridine-induced purine release from isolated rat hypothalamic synaptosomes.
Several drugs claimed to protect against anoxic damage to the brain and/or to aleviate symptoms of senility were tested for their… 
1992
1992
Veratridine causes the Ca2+-dependent increase in diacylglycerol formation and translocation of protein kinase C to membranes in cultured bovine adrenal medullary cells
SummaryOur previous studies suggested that protein kinase C is involved in the veratridine (an activator of voltage-dependent Na… 
Highly Cited
1986
Highly Cited
1986
Permissive effect of dexamethasone on the increase of proenkephalin mRNA induced by depolarization of chromaffin cells.
In cultured bovine chromaffin cells, changes in the dynamic state of enkephalin stores elicited experimentally were studied by… 
1982
1982
Uptake of [N-Me-3H]-choline by synaptosomes from the central nervous system of Locusta migratoria.
The accumulation of 3H-choline by isolated synaptosomes from the central nervous system of locust was studied at concentrations… 
Highly Cited
1981
Highly Cited
1981
Ionic channels involved in the LHRH and SRIF release from rat mediobasal hypothalamus.
A superfusion system was used in order to investigate the ionic requirements of luteinizing hormone releasing hormone (LHRH) and… 
1981
1981
Differentiation of the fast Na+ channel in embryonic heart cells: interaction of the channel with neurotoxins.
The sensitivity of embryonic cardiac cells to tetrodotoxin (TTX) increases with age. At the early embryonic stage, the maximum… 
1979
1979
Release of catecholamines from perfused cat adrenal gland by veratridine.
Experiments were undertaken to verify the existence of fast sodium channels in the adrenal chromaffin cell membrane and to assess… 
1977
1977
Efflux of 5-hydroxytryptamine from synaptosomes of rat cerebral cortex.
The efflux of 3H-5-HT from a crude synaptosome preparation of the cerebral cortex of reserpinized rats was examined. The… 
Highly Cited
1972
Highly Cited
1972
Accumulation of adenosine 3':5'-cyclic monophosphate in clonal glial cells: labeling of intracellular adenine nucleotides with radioactive adenine.
The accumulation of endogenous adenosine 3':5'-cyclic phosphate (cAMP) and of [(14)C]cAMP, derived from nucleotides labeled by… 
1943
1943
STUDIES ON VERATRUM ALKALOIDS III. QUALITATIVE AND QUANTITATIVE DIFFERENCES IN THE ACTION OF CEVINE AND VERATRIDINE
The qualitative and quantitative differences between cevine and its veratric acid ester, veratridine, on the isolated frog heart… 
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