Vascular Endothelial Growth Factor A

Known as: Vasculotropin, VEGF-A, Vascular Endothelial Growth Factor-A 
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth… (More)
National Institutes of Health

Related topics

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33 relations
Endothelial Growth FactorsHeparin Binding Growth FactorIn BloodPTK787/ZK 222584
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Broader (2)

Growth FactorVascular Endothelial Growth Factors

Narrower (5)

Recombinant Vascular Endothelial Growth FactorVEGF protein, humanVEGF165 protein, humanvammin protein, Vipera ammodytes ammodytes
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Papers overview

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Highly Cited
2006
Highly Cited
2006
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma.
PURPOSE Renal cell carcinoma (RCC) is characterized by loss of von Hippel Lindau tumor suppressor gene activity, resulting in… (More)
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Review
2004
Review
2004
Vascular endothelial growth factor as a target for anticancer therapy.
The development of a vascular supply is a critical factor in the growth and metastatic spread of malignant tumors. Of the… (More)
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Highly Cited
2001
Highly Cited
2001
Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability.
Nitric oxide (NO) plays a critical role in vascular endothelial growth factor (VEGF)-induced angiogenesis and vascular… (More)
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Highly Cited
2001
Highly Cited
2001
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
The role of bone marrow (BM)-derived precursor cells in tumor angiogenesis is not known. We demonstrate here that tumor… (More)
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Review
2001
Review
2001
Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family.
The central role of vascular endothelial growth factor (VEGF) in angiogenesis in health and disease makes it attractive both as a… (More)
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Highly Cited
2001
Highly Cited
2001
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
Hypoxia stimulates angiogenesis through the binding of hypoxia-inducible factors to the hypoxia-response element in the vascular… (More)
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Highly Cited
1998
Highly Cited
1998
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells.
Interendothelial junctions play an important role in the regulation of endothelial functions, such as vasculogenesis… (More)
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Highly Cited
1996
Highly Cited
1996
Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody.
The hyperpermeability of tumor vessels to macromolecules, compared with normal vessels, is presumably due to vascular endothelial… (More)
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Highly Cited
1992
Highly Cited
1992
Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.
The vascular endothelial growth factor (VEGF) family encompasses four polypeptides that result from alternative splicing of mRNA… (More)
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Highly Cited
1989
Highly Cited
1989
Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.
Vascular permeability factor (VPF) is an Mr 40-kD protein that has been purified from the conditioned medium of guinea pig line… (More)
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