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Protective immunity against Mycobacterium tuberculosis depends on the generation of a TH1-type cellular immune response… Expand In animals, effective immune responses against malignancies and against several infectious pathogens, including malaria, are… Expand Vaccinia virus produces four different types of virion from each infected cell called intracellular mature virus (IMV… Expand BACKGROUND
Human papillomavirus (HPV) infection, especially with type 16 or 18, is associated with cervical cancer. Two HPV… Expand Modified vaccinia Ankara (MVA), a highly attenuated vaccinia virus strain that has been safety tested in humans, was evaluated… Expand The complete DNA sequence of the genome of vaccinia virus has been determined. The genome consisted of 191,636 bp with a base… Expand DNA coding for bacteriophage T7 RNA polymerase was ligated to a vaccinia virus transcriptional promoter and integrated within the… Expand We constructed a plasmid coexpression vector that directs the insertion of a foreign gene of interest together with the… Expand Rabies is one of the oldest diseases known to man, but its successful control has remained elusive. Although effective vaccines… Expand Foreign DNA was inserted into two nonessential regions of the vaccinia virus genome by homologous recombination in cells infected… Expand