• Publications
  • Influence
Prospects for hepatitis C virus therapeutics: levovirin and viramidine as improved derivatives of ribavirin.
  • J. Watson
  • Medicine
  • Current opinion in investigational drugs
  • 1 May 2002
Ribavirin, in combination with interferons, has proved clinically useful for the treatment of hepatitis C virus (HCV) infection despite uncertainty as to its true mechanism of action. ItsExpand
  • 46
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A Novel, Highly Selective Inhibitor of Pestivirus Replication That Targets the Viral RNA-Dependent RNA Polymerase
ABSTRACT We report on the highly potent and selective antipestivirus activity of 5-[(4-bromophenyl)methyl]-2-phenyl-5H-imidazo[4,5-c]pyridine (BPIP). The 50% effective concentration (EC50) forExpand
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  • PDF
Unruly Bodies: Autoethnography and Authorization in Nafissatou Diallo's 'De Tilene au Plataeu (A Dakar Childhood)
Cette analyse du De Tilene au Plateau de Diallo considere ce texte a la lumiere des efforts de l'ecrivain pour detruire les frontieres qui existent entre les ecritures autobiographiques etExpand
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Characterization of a novel antibacterial agent that inhibits bacterial translation.
Bacterial protein synthesis is the target for several classes of established antibiotics. This report describes the characterization of a novel translation inhibitor produced by the soil bacteriumExpand
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Hepatitis C virus RNA quantitation and degradation studies in whole blood samples in vitro
Hepatitis C virus (HCV) qualitative and quantitative polymerase chain reaction (PCR) tests have evolved from specialist research tools into tests that are widely used in routine clinical practice.Expand
  • 3
SAR studies on dihydropyrimidinone antibiotics.
  • L. Xu, L. Zhang, +12 authors C. U. Kim
  • Medicine, Chemistry
  • Bioorganic & medicinal chemistry letters
  • 15 March 2011
There is an urgent need for the development of novel antimicrobial agents that offer effective treatment against MRSA. Using a new class of dipeptide antibiotic TAN-1057A/B as lead, we designed,Expand
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Morphometric and molecular analysis of two distinct forms of Pseudocrossidium crinitum
Two distinct forms of Pseudocrossidium crinitum (Bryophyta) exista form with a white hair point on the leaf, and one with a yellow hair point on the leaf. The white and yellow forms exist in similarExpand
Daniel de foe
Viral RNA-Dependent RNA Polymerase Pestivirus Replication That Targets the A Novel , Highly Selective Inhibitor of
2006, 80(1):149. DOI: 10.1128/JVI.80.1.149-160.2006. J. Virol. Johan Neyts Julia Watson, Erik De Clercq, Gerhard Puerstinger and Koenen, Pierre Kerkhofs, Ruben O. Donis, Piet Herdewijn, CarineExpand