VTCN1 gene

Known as: B7H4, B7X, B7 HOMOLOG 4 
This gene plays a role in the regulation of cell-mediated immunity.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2017
0102020032017

Papers overview

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2009
2009
B7-H4 is an immunoglobulin superfamily molecule and shown to be inhibitory for T-cell responses. To explore physiologic roles of… (More)
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Highly Cited
2007
Highly Cited
2007
B7-H4 is a recently identified B7 family member. We previously showed that ovarian tumor and associated macrophages expressed B7… (More)
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Highly Cited
2007
Highly Cited
2007
B7-H3 and B7x are recently discovered members of the B7-CD28 family thought to dampen peripheral immune responses via negative… (More)
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Highly Cited
2006
Highly Cited
2006
Multiple modes of suppressive mechanisms including IL-10 are thought to be implicated in CD4+CD25+ regulatory T (Treg) cell… (More)
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Highly Cited
2006
Highly Cited
2006
B7-H4 is a recently described B7 family coregulatory ligand that has been implicated as an inhibitor of T cell-mediated immunity… (More)
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Highly Cited
2006
Highly Cited
2006
Using cDNA database mining strategies and real-time quantitative reverse transcription-PCR, we identified B7-H4 as a novel gene… (More)
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Highly Cited
2006
Highly Cited
2006
Inhibitory regulatory functions of B7-H3 and B7-H4 regarding T-cell activation have been reported recently. Little is known about… (More)
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Highly Cited
2005
Highly Cited
2005
B7-H4 protein is expressed on the surface of a variety of immune cells and functions as a negative regulator of T cell responses… (More)
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Highly Cited
2003
Highly Cited
2003
We identify a B7 family molecule, B7-H4, by protein sequence analysis and comparative molecular modeling. While B7-H4 mRNA is… (More)
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Highly Cited
2003
Highly Cited
2003
T cell activation by antigen-presenting cells (APC) is regulated by positive and negative costimulatory molecules in the B7… (More)
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