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Significance of M2-polarized tumor-associated macrophage in pancreatic cancer.
BACKGROUND The roles of infiltrating macrophages within the tumor microenvironment are complex because of their functional variety. The aim of this study is to examine the role and prognosticExpand
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Human papillomavirus detected in female breast carcinomas in Japan
To investigate the aetiological role of human papillomavirus (HPV) in breast cancer, we examined the presence, genotype, viral load, and physical status of HPV in 124 Japanese female patients withExpand
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Sentinel node mapping for gastric cancer: a prospective multicenter trial in Japan.
PURPOSE Complicated gastric lymphatic drainage potentially undermines the utility of sentinel node (SN) biopsy in patients with gastric cancer. Encouraged by several favorable single-institutionExpand
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Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis
Background and objective About 9% of gastric carcinomas have Epstein–Barr virus (EBV) in the tumour cells, but it is unclear whether viral presence influences clinical progression. We thereforeExpand
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Trans-Oral Video-Assisted Neck Surgery (TOVANS). A new transoral technique of endoscopic thyroidectomy with gasless premandible approach
BackgroundEndoscopic thyroidectomy is a well-established surgical technique. We have been utilizing precordial video-assisted neck surgery (VANS) with a gasless anterior neck skin lifting method.Expand
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Slug Expression in the E-cadherin preserved tumors is related to prognosis in patients with esophageal squamous cell carcinoma.
PURPOSE The expression of E-cadherin correlates with the development, progression, and metastasis of esophageal squamous cell carcinoma (ESCC). Slug, a member of the snail family of transcriptionalExpand
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Genomic Landscape of Esophageal Squamous Cell Carcinoma in a Japanese Population.
BACKGROUND & AIMS Esophageal squamous cell carcinoma (ESCC) is the predominant form of esophageal cancer in Japan. Smoking and drinking alcohol are environmental risk factors for ESCC, whereas singleExpand
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PRMT5 is required for lymphomagenesis triggered by multiple oncogenic drivers.
UNLABELLED Protein arginine methyltransferase 5 (PRMT5) has been implicated as a key modulator of lymphomagenesis. Whether PRMT5 has overt oncogenic function in the context of leukemia/lymphoma andExpand
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Prognostic value of intratumoral natural killer cells in gastric carcinoma
Natural killer (NK) cells are a group of effector cells that act nonspecifically against tumor cells. The correlation between intratumoral NK cell infiltration and clinicopathologic features remainsExpand
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Galectin-3 expression in various thyroid neoplasms and its possible role in metastasis formation.
Galectin-3 is a member of the beta-galactoside-binding protein family that plays an important role in cell-cell adhesion and in cell-matrix interaction. We have examined the expression of galectin-3Expand
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